Dorin Sendrescu

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This paper presents the design and the analysis of some nonlinear adaptive control strategies for a class of anaerobic depollution processes that are carried out in continuous stirred tank bioreactors. The controller design is based on the input-output linearization technique. The adaptive control structure is based on the nonlinear model of the process and(More)
This paper addresses the problem of Bond Graph modelling of nonlinear bioprocesses. The rules for the design of pseudo Bond Graph models of some prototype bioprocesses — one batch and one continuous process — are obtained using the reaction schemes and the analysis of biochemical phenomena. These rules are applied in order to design the Bond(More)
The paper presents the design and analysis of some nonlinear and neural adaptive control strategies for a class of time-varying and nonlinear processes. In fact, a direct adaptive controller based on a radial basis function neural network used as online approximator to learn the time-varying characteristics of process parameters is developed and then is(More)
1 Návrh robustného decentralizovaného riadenia pomocou LMI In this paper, the robust optimal model matching control design method is applied to a flexible beam Quanser experiment. The neglected nonlinearities of the real experiment in the controller design step lead to important differences between the simulation and experimental results, including(More)
This paper presents an approach on the bond graph modelling applied to a Quanser rotary inverted pendulum experiment followed by the computation of the mathematical model. The system was decomposed into subsystems that were modelled separately. The obtained subsystems generated submodels and the overall model was then built up by combining these separate(More)
Monoclonal antibodies (mAbs) are at present one of the fastest growing products of pharmaceutical industry, with widespread applications in biochemistry, biology, and medicine. The operation of mAbs production processes is predominantly based on empirical knowledge, the improvements being achieved by using trial-and-error experiments and precedent(More)
The paper presents the results of mathematical modeling using bond graph methodology applied to cells growing process in pharmaceutical industry. Largely used at industrial scale, the mammalian cell culture represents an important sector with intensive dynamic that requires continuous optimization due to evolution and transformations of medical(More)