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In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy(More)
The cryopreservation of ovarian tissue has been reported to affect the development of preantral follicles. However, the effect of cryopreservation of ovarian tissue on the development of primordial follicles remains to be elucidated. This study was conducted to evaluate the effect of cryopreservation on the development of frozen-thawed mouse primordial(More)
Cryopreservation of ovarian tissue has been reported to delay the development of preantral follicles by temporary suppression of granulosa cell proliferation during in vitro culture. This delay might be overcome by treatment with activin A and/or IGF-I, known to stimulate granulosa cell proliferation. However, the effects of these growth factors, on delayed(More)
OBJECTIVE This study estimated an association between cognitive impairment and bone mineral density (BMD), a surrogate marker for cumulative estrogen exposure. METHODS This cross-sectional study included 120 postmenopausal women. Based on neuropsychological tests, the women were classified into three groups: those with subjective memory impairment (SMI, n(More)
A few studies have investigated the effects of laparoscopic cystectomy for endometrioma on ovarian reserve using serum anti-Müllerian hormone (AMH) levels and have shown inconsistent results. This prospective study was performed to estimate early changes in serum AMH after laparoscopic surgery for endometrioma. In 27 women aged 21-46 years who underwent(More)
OBJECTIVE This paper aims to explore women's experiences of premenstrual symptoms in three Asian countries and the factors affecting the prevalence of these symptoms. STUDY DESIGN Cross-sectional survey. A sample of 1202 women aged 15-49 years were recruited by random sampling in Hong Kong, Pakistan and Thailand. Main outcome measures The interviewer used(More)
STUDY OBJECTIVE To analyze the clinical characteristics of young Korean female children and adolescents who underwent surgery because of adnexal masses during the last 14 years. DESIGN Retrospective cohort study (Canadian Task Force classification II-2). SETTING University hospital. PATIENTS Three hundred ninety-six young female patients aged 20 years(More)
OBJECTIVES To evaluate the effect of rec-FSH on the ovarian follicular environment in controlled ovarian hyperstimulation (COH) cycle, we compared the expression of the markers that have been reported to reflect the follicle health. STUDY DESIGN A total of 31 women (<35 years) with normal ovarian function were allocated to three different COH protocols(More)
Purpose: The aim was to evaluate whether the expression of cyclin D2 mRNA in human luteinized granulosa cells correlates with the clinical parameters of women undergoing in vitro fertilization–embryo transfer (IVF-ET) programs. Methods: Using reverse transcriptase–polymerase chain reaction (RT-PCR) techniques, the cyclin D2 mRNA in human luteinized(More)
OBJECTIVE The rhizome of the Cimicifuga racemosa plant (commonly known as black cohosh) has been used for menopausal complaints. Studies regarding the cardiovascular effects of black cohosh are lacking. We investigated the effect of black cohosh on the plasminogen activator system in cultured vascular smooth muscle cells (VSMCs). METHODS VSMCs were(More)