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STUDY OBJECTIVES An ideal biomarker for sleep should change rapidly with sleep onset, remain at a detectably differential level throughout the sleep period, and exhibit a rapid change with waking. Currently, no molecular marker has been identified that exhibits all three properties. This study examined three substances (lactate, glucose, and glutamate) for(More)
We have been studying the development of hypertension in spontaneously hypertensive rats (SHR) fed a low protein diet. The effects of a low protein diet upon food and water intake were examined. Body weight gain, food and water intake were measured in three to twenty-three week-old SHR and Wistar Kyoto rats (WKY) fed diets containing 8%, 15% or 25% casein.(More)
Sirenia ® Beginning January 15, all Pinnacle products will be shipped with Sirenia ® , our new acquisition software package. Sirenia ® will seamlessly integrate all of our EEG, biosensor, and video systems. Beta versions of the software are currently available online. Sirenia ® supports the integration of third-party data streams via a National Instruments(More)
A vital component to a successful animal surgery is providing the animal with proper post­surgery care. To promote healthy recovery, Pinnacle advises waiting 5­7 days before beginning experiments. This includes attempting to plug in a headstage or preamplifier into the animal's EEG/EMG headmount or inserting a biosensor into a cannula. When housing animals(More)
Reminder Pinnacle recently released Version 1.2.3 of our Sirenia ® sof tware. To ensure that y ou're getting the most f rom this sof tware program, we recommend regularly updating y our sof tware. The new v ersion can be downloaded f or f ree f rom our website. Surgery Tip Working with Wire Leads: When arranging and placing screws with wire leads, it is(More)
For recording real-time changes in lactate concentration in the CNS. In vitro and in vivo lactate biosensor data COMING SOON Wireless EEG/EMG/BIO 2 EEG Channels 1 EMG Channel 1 Biosensor Channel We are pleased to present the first edition of the Pinnacle newsletter. In this space, you will find surgical tips and answers to frequently asked technical(More)
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