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SiRNA Directed Against Annexin II Receptor Inhibits Angiogenesis via Suppressing MMP2 and MMP9 Expression
Background/Aims: Annexin II receptor (AXIIR) is able to mediate Annexin II signal and induce apoptosis, but its role in angiogenesis remains unclear. This study tries to investigate the role of AXIIRExpand
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Annexin A2 silencing enhances apoptosis of human umbilical vein endothelial cells in vitro.
OBJECTIVE To study the effects of inhibited Annexin A2 (ANXA2) on human umbilical vein endothelial cells (HUVECs) in vitro. METHODS Short hairpin RNA (shRNA) targeting ANXA2 was designed and clonedExpand
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Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy
Purpose Annexin A2 has been shown to play a role in many neovascularization diseases. We investigated the effect of vascular endothelial growth factor (VEGF) on annexin A2 expression and relatedExpand
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Annexin A2 promotes choroidal neovascularization by increasing vascular endothelial growth factor expression in a rat model of argon laser coagulation-induced choroidal neovascularization.
BACKGROUND Choroidal neovascularization (CNV) is a common cause of visual loss in the elderly patients with age-related macular degeneration and represents the growth of subretinal new vessels in theExpand
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Hexabromocyclododecanes promoted autophagy through the PI3K/Akt/mTOR pathway in L02 cells.
As additive brominated flame retardants, hexabromocyclododecanes (HBCDs) are being widely used in diverse artificial materials and products, including thermal insulation building materials, housingsExpand
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UMSC-derived exosomes promote retinal ganglion cells survival in a rat model of optic nerve crush
Traumatic optic neuropathy or glaucoma lead to retinal ganglion cells loss and cause blindness, and there is no effective therapy strategy by far. Mesenchymal cells from the Wharton's jelly of theExpand
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Laser capture microdissection-based single-cell RNA sequencing reveals optic nerve crush-related early mRNA alterations in retinal ganglion cells
Retinal ganglion cells (RGC) are the primary cell type injured in a variety of diseases of the optic nerve, and the early changes of RGC’s RNA profiling may be important to understand the mechanismExpand
Laser Capture Microdissection-Based RNA Microsequencing Reveals Optic Nerve Crush-Related Early mRNA Alterations in Retinal Ganglion Cell Layer
Purpose To establish a method of laser capture microdissection (LCM) and RNA microsequencing for exploring optic nerve crush (ONC)–related early mRNA alterations in retinal ganglion cell (RGC) layer.Expand
Clinical effects on retrograde intubation of silicone lacrimal drainage tube compared with dacryocystorhinostomy for chronic dacryocystitis
Objective To compare the effect of retrograde intubation of silicone lacrimal drainage (group A) and dacryocystorhinostomy (group B) in treating chronic dacryocystitis.Methods Chronic dacryocystitisExpand
Effect of intraocular anti-VEGF on cystoid macular edema associated with Henoch-Schonlein purpura-a case report
Background To report a bilateral cystoid macular edema associated with Henoch-Schonleinpurpura. Case presentation A 21-year-old man presented a bilateral, painless, and bilateral blurred vision for 5Expand