Dongsung Kim

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Hexanucleotide repeat expansion in the C9orf72 gene is a leading cause of frontotemporal lobar degeneration (FTLD) with amyotrophic lateral sclerosis (ALS). Reduced expression of C9orf72 has been proposed as a possible disease mechanism. However, the cellular function of C9orf72 remains to be characterized. Here we report the identification of two binding(More)
This paper describes the design and implementation of a home network system using UPnP middleware and an embedded interface device. The developed home network system comprises a home server program, appliance emulators; (e.g., for l'K refrigerator, and airconditioner), and an embedded interface device for networked home appliances.
The use of virtualization is rapidly expanding from server consolidation to various computing systems including PC, multimedia set-top box and gaming console. However, different from the server environment, timeliness response for the external input is an essential property for the user-interactive applications. To provide timeliness scheduling of virtual(More)
The Mec1/Tel1 kinases (human ATR/ATM) play numerous roles in the DNA replication stress response. Despite the multi-functionality of these kinases, studies of their in vivo action have mostly relied on a few well-established substrates. Here we employed a combined genetic-phosphoproteomic approach to monitor Mec1/Tel1 signaling in a systematic, unbiased,(More)
In this paper, we propose a fully automatic method for vertebra segmentation in the CT volume data. The method constructs 3D fences that separate adjacent vertebrae from valley-emphasized Gaussian images. Initial curves for the 3D fences are extracted from intervertebral discs, detected with anatomical characteristics, then optimized using a deformable(More)
Aerobic glycolysis or the Warburg Effect (WE) is characterized by the increased metabolism of glucose to lactate. It remains unknown what quantitative changes to the activity of metabolism are necessary and sufficient for this phenotype. We developed a computational model of glycolysis and an integrated analysis using metabolic control analysis (MCA),(More)
A new kinorhynch species, Condyloderes megastigma sp. nov., is described from the Korea Strait. The new species is characterized by the presence of 16 placids with either eight, four, or two knobby projections, middorsal and lateroventral acicular spines on segments 1 to 9, lateroventral cuspidate spines on segment 2 in females only, but otherwise(More)
Meristoderes is the most recently described kinorhynch genus and has until now only accommodated its type species M. macracanthus from the Mediterranean and M. galatheae from the Solomon Islands in Southeast Asia. The present contribution is an account on the genus based on samples from the ongoing exploration of the kinorhynch fauna in coastal and subtidal(More)
We introduce an efficient method for recognition and localization of generic objects for robot navigation, which works on real scenes. The generic objects used in our experiments are desks and doors as they are suitable landmarks for navigation. The recognition method uses significant surfaces and accompanying functional evidence for recognition of such(More)