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Bioactivation of 1-chloro-2-hydroxy-3-butene, an in vitro metabolite of 1,3-butadiene, by rat liver microsomes.
- Ye Wang, Y. Yu, Yang Luan, J. An, Dongni Yin, Xin-Yu Zhang
- Chemistry, Medicine
- Chemico-biological interactions
- 25 February 2018
1-Chloro-2-hydroxy-3-butene (CHB) is an in vitro metabolite of 1,3-butadiene, a rodent/human carcinogen. To search for an approach detecting CHB in vivo, it is vital to obtain a full understanding of… Expand