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RIOK3 was initially characterized as a homolog of Aspergillus nidulans sudD and showed down-regulation at the invasive front of malignant melanomas, but the molecular mechanism remains elusive. Here, we report that overexpression of RIOK3 inhibits TNFα-induced NF-κB activation, but down-regulation of endogenous RIOK3 expression by siRNA potentiates it. A(More)
BACKGROUND To screen the differential expression genes of KANLAITE in anti-tumor metastasis. METHODS mRNA was extracted and purified from the lung of the mouse with LA795 lung metastasis, hybridized respectively on 4 096-gene chip. cDNA microarray was scanned for the fluorescent signals and analyzing difference expression. RESULTS Twenty-seven(More)
In this paper, we propose a new method for finding global optimum of continuous optimization problems, namely Level-Value Estimation algorithm(LVEM). First we define the variance function v(c) and the mean deviation function m(c) with respect to a single variable (the level value c), and both of these functions depend on the optimized function f (x). We(More)
—In this paper we propose an appealing inexact proximal alternating directions method (abbreviated as In-PADM) for solving a class of monotone variational inequalities with certain special structure, and this structure under consideration is common in practice. We prove convergence of In-PADM method while the inexact term is arbitrary but satisfied some(More)