Overexpression and molecular characterization of Aga50D from Saccharophagus degradans 2-40: an exo-type β-agarase producing neoagarobiose
- Hee Taek Kim, Saeyoung Lee, I. Choi
- BiologyApplied Microbiology and Biotechnology
- 1 March 2010
Identification and analysis of the reaction product by mass spectrometry and 13C NMR showed that Aga50D had unique exo-lytic activity and was able to produce neoagarobiose directly from agarose.
Blockade of Nuclear Factor-κB Signaling Pathway and Anti-Inflammatory Activity of Cardamomin, a Chalcone Analog from Alpinia conchigera
- Jeong-Hyung Lee, Haeng-Sun Jung, Jung Joon Lee
- Biology, ChemistryJournal of Pharmacology and Experimental…
- 1 January 2006
Cardamomin is demonstrated to be valuable candidate for the intervention of NF-κB-dependent pathological condition such as inflammation and rescued C57BL/6 mice from LPS-induced mortality in conjunction with decreased serum level of TNF-α.
Cytotoxic and antineoplastic activity of timosaponin A-III for human colon cancer cells.
- You-Jin Kang, Hwa-Jin Chung, Sang Kook Lee
- Biology, ChemistryJournal of Natural Products
- 3 March 2011
Treatment with compound 1 for four weeks significantly suppressed tumor growth in athymic nude mice bearing HCT-15 cells, without any overt toxicity.
Cytotoxic flavone analogues of vitexicarpin, a constituent of the leaves of Vitex negundo.
- F. Díaz, D. Chávez, A. Kinghorn
- Biology, ChemistryJournal of Natural Products
- 7 May 2003
Bioassay-guided fractionation of the chloroform-soluble extract of the leaves of Vitex negundo led to the isolation of the known flavone vitexicarpin (1), which exhibited broad cytotoxicity in a…
Natural inhibitors of carcinogenesis.
- A. Kinghorn, B. Su, J. Pezzuto
- Chemistry, BiologyPlanta Medica
- 1 August 2004
Based on this large pool of potential cancer chemopreventive compounds, structure-activity relationships are discussed in terms of the quinone reductase induction ability of flavonoids and withanolides and the cyclooxygenase-1 and -2 inhibitory activities of flavanones, flavones and stilbenoids.
Protective effect of caffeic acid against beta-amyloid-induced neurotoxicity by the inhibition of calcium influx and tau phosphorylation.
- D. Sul, Hyo-shin Kim, Dongho Lee, S. Joo, K. Hwang, So-Young Park
- BiologyLife Science
- 27 February 2009
Inhibitory constituents of the heartwood of Dalbergia odorifera on nitric oxide production in RAW 264.7 macrophages.
- C. Lee, Jin Woo Lee, B. Hwang
- ChemistryBioorganic & Medicinal Chemistry Letters
- 15 July 2013
Lignans from Arctium lappa and their inhibition of LPS-induced nitric oxide production.
- So Young Park, S. Hong, B. Hwang
- ChemistryChemical and pharmaceutical bulletin
- 2007
A new butyrolactone sesquilignan, isolappaol C (1) was determined by spectral analysis including 1D- and 2D-NMR, and strongly inhibited NO production in the LPS-stimulated RAW264.7 cells.
Synergistic Antimicrobial Activity of Metabolites Produced by a Nonobligate Bacterial Predator
- C. Cain, Dongho Lee, J. Falkinham
- BiologyAntimicrobial Agents and Chemotherapy
- 1 July 2003
Both maculosin and banegasine were found to potentiate the antimicrobial activity of pyrrolnitrin, which appears to represent a new genus and species of eubacteria, Aristabacter necator, due to synergism between metabolites.
Protuboxepins A and B and protubonines A and B from the marine-derived fungus Aspergillus sp. SF-5044.
- Sang Un Lee, Yukihiro Asami, Dongho Lee, Jae-Hyuk Jang, J. Ahn, H. Oh
- ChemistryJournal of Natural Products
- 2 March 2011
Two new oxepin-containing (1 and 2) and two diketopiperazine-type alkaloids (3 and 4) have been isolated from an EtOAc extract of the marine-derived fungus Aspergillus sp. SF-5044. The structures of…
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