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In papillary thyroid carcinoma, expression by immunohistochemistry of BRAF V600E, PD-L1, and PD-1 is closely related
- Yanhua Bai, T. Guo, +6 authors K. Kakudo
- Medicine
- Virchows Archiv
- 12 April 2018
Immune checkpoint inhibitor therapies targeting PD-L1/PD-1 have been shown to be effective in treating several types of human cancer. In papillary thyroid carcinoma (PTC), little is known about the… Expand
Expression of aquaporin3 in human neoplastic tissues
- Dongfeng Niu, T. Kondo, +6 authors R. Katoh
- Biology, Medicine
- Histopathology
- 1 October 2012
Niu D, Kondo T, Nakazawa T, Yamane T, Mochizuki K, Kawasaki T, Matsuzaki T, Takata K & Katoh R
(2012) Histopathology 61, 543–551
PD-L1 and PD-1 expression are correlated with distinctive clinicopathological features in papillary thyroid carcinoma
- Yanhua Bai, Dongfeng Niu, +10 authors K. Kakudo
- Biology, Medicine
- Diagnostic Pathology
- 3 October 2017
BackgroundImmune checkpoint blockade targeting PD-1/PD-L1 has shown efficacy in several types of cancers. However, the correlation between PD-L1/PD-1 expression and the specific clinicopathological… Expand
Carcinoid Arising From the Teratomatous Bronchial Mucosa in a Mature Cystic Teratoma of the Ovary: A Case Report
- Dongfeng Niu, Z. Li, L. Sun, D. Cao
- Medicine
- International journal of gynecological pathology…
- 1 August 2017
Primary ovarian carcinoids are relatively uncommon, either pure (monodermal teratomas) or in association with mature cystic teratomas. Here we reported a unique case of carcinoid arising from the… Expand
Epigenetic silencing of TTF-1/NKX2-1 through DNA hypermethylation and histone H3 modulation in thyroid carcinomas
- T. Kondo, T. Nakazawa, +7 authors R. Katoh
- Biology, Medicine
- Laboratory Investigation
- 8 June 2009
Thyroid transcription factor-1 (TTF-1), also known as NKX2-1, is a homeodomain containing transcriptional factor identified in thyroid, lung and central nervous system. In the thyroid, TTF-1 is… Expand
Differential Expression of Aquaporins and Its Diagnostic Utility in Thyroid Cancer
- Dongfeng Niu, T. Kondo, +7 authors R. Katoh
- Biology, Medicine
- PloS one
- 10 July 2012
Background Aquaporin3 (AQP3) and Aquaporin4 (AQP4) play a major role in transcellular and transepithelial water movement as water channel membrane proteins. Little is known of their expression and… Expand
Global histone modification of histone H3 in colorectal cancer and its precursor lesions.
- T. Nakazawa, T. Kondo, +7 authors R. Katoh
- Biology, Medicine
- Human pathology
- 1 June 2012
Chromatin remodeling through histone modification is an important mechanism of epigenetic gene dysregulation in human cancers. However, little is known about global alteration of histone status… Expand
RET/PTC rearrangements arising from a small population of papillary thyroid carcinoma cells, possible candidate for passenger mutation
- T. Nakazawa, S. Murata, +6 authors R. Katoh
- Biology, Medicine
- Virchows Archiv
- 3 June 2009
RET rearrangements (RET/PTC) is a major genetic alteration in papillary thyroid carcinomas. However, the prevalence of RET/PTC differs considerably among investigators, and its impact on cancer… Expand
Involvement of centrosomes in nuclear irregularity of thyroid carcinoma cells
- Dongfeng Niu, S. Murata, +6 authors R. Katoh
- Biology, Medicine
- Virchows Archiv
- 9 July 2009
Nuclear irregularities including nuclear pseudoinclusions and nuclear grooves are characteristic of papillary thyroid carcinoma cells and are regarded as important diagnostic clues in histopathology.… Expand
SATB2 Shows Different Profiles Between Appendiceal Adenocarcinomas Ex Goblet Cell Carcinoids and Appendiceal/Colorectal Conventional Adenocarcinomas: An Immunohistochemical Study With Comparison to…
Background Special AT-rich sequence-binding protein 2 (SATB2) is a novel marker for colorectal adenocarcinomas but little is known about its expression in appendiceal adenocarcinomas. We aim to… Expand