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Organismal aging is influenced by a multitude of intrinsic and extrinsic factors, and heterochromatin loss has been proposed to be one of the causes of aging. However, the role of heterochromatin in animal aging has been controversial. Here we show that heterochromatin formation prolongs lifespan and controls ribosomal RNA synthesis in Drosophila. Animals(More)
The proto-oncoprotein Raf is pivotal for mitogen-activated protein kinase (MAPK) signaling, and its aberrant activation has been implicated in multiple human cancers. However, the precise molecular mechanism of Raf activation, especially for B-Raf, remains unresolved. By genetic and biochemical studies, we demonstrate that phosphorylation of tyrosine 510 is(More)
A Bayer pattern image codec method based on Wyner-Ziv structure is proposed in this paper. At the encoder the pixel of Bayer pattern image is converted into four component images by means of structural separation and transformation. Three of them are transformed into frequency domain by the discrete cosine transform. We extended the Lloyd iterative(More)
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