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In this study, we demonstrated a new airway Ag sampling site by analyzing tissue sections of the murine nasal passages. We revealed the presence of respiratory M cells, which had the ability to take up OVA and recombinant Salmonella typhimurium expressing GFP, in the turbinates covered with single-layer epithelium. These M cells were also capable of taking(More)
OBJECTIVE To determine the predictors affecting treatment outcome after application of the mandibular advancement device (MAD). DESIGN Retrospective analysis. SETTING Tertiary care university hospital. PATIENTS A total of 76 patients (68 men and 8 women) who were treated with the MAD for obstructive sleep apnea (OSA) were included from September 2005(More)
OBJECTIVES Videostrobokymography (VSK) has recently been introduced. The aim of this study was to analyze vibratory patterns and objective parameters in various benign vocal fold lesions using VSK and to examine the efficacy of VSK in clinical applications. MATERIAL AND METHODS Using VSK, we analyzed the vibration patterns of normal vocal folds, various(More)
The research establishes a comparison between the European Foundation for Quality Management (EFQM) business excellence model and the Intellectual Capital (IC) management model. Results indicate that the IC management model covers the criteria of the EFQM excellence model. Moreover, the authors address three similarities and three differences between two(More)
OBJECTIVES The internet has become an important source of medical information and a great amount of information related to allergic rhinitis (AR) is available on the internet. However, the quality of this information is still a matter of debate. Therefore, this study was conducted to assess the AR-related information on Korean websites. METHODS The key(More)
Mucosally ingested and inhaled antigens are taken up by membranous or microfold cells (M cells) in the follicle-associated epithelium of Peyer's patches or nasopharynx-associated lymphoid tissue. We established a novel M cell-specific monoclonal antibody (mAb NKM 16-2-4) as a carrier for M cell-targeted mucosal vaccine. mAb NKM 16-2-4 also reacted with the(More)
CONCLUSION Sublingual immunotherapy (SLIT) with house dust mite (HDM) extracts in school-age children and adolescents seems to be as effective as in adults. SLIT could be recommended as a therapeutic modality in pediatric allergic rhinitis (AR) patients sensitized to HDMs. OBJECTIVES To investigate the efficacy of HDM SLIT in pediatric patients with AR.(More)
CONCLUSION In a retrospective study of 239 cases of fungal sinusitis, noninvasive paranasal sinus aspergillosis was most common and successfully treated by endoscopic sinus surgery (ESS) with postoperative sinus irrigation. For the treatment of fungal sinusitis, ESS with or without antifungal agents and control of predisposing factors for secondary cases(More)
BACKGROUND It is suggested that polysensitized patients might not benefit from specific allergic rhinitis immunotherapy as much as monosensitized patients, although further research on this subject is needed. OBJECTIVE To compare the efficacy of sublingual immunotherapy (SLIT) with standardized house dust mite extract in monosensitized and polysensitized(More)