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In this study, we demonstrated a new airway Ag sampling site by analyzing tissue sections of the murine nasal passages. We revealed the presence of respiratory M cells, which had the ability to take up OVA and recombinant Salmonella typhimurium expressing GFP, in the turbinates covered with single-layer epithelium. These M cells were also capable of taking(More)
The research establishes a comparison between the European Foundation for Quality Management (EFQM) business excellence model and the Intellectual Capital (IC) management model. Results indicate that the IC management model covers the criteria of the EFQM excellence model. Moreover, the authors address three similarities and three differences between two(More)
2351 Mucosa-associated lymphoid tissues (MALTs), including nasopharynx-associated lymphoid tissue (NALT) and Peyer's patches (PPs), are gateways for the uptake of inhaled and in-gested antigens from the lumen of the aerodi-gestive tract, and are considered to be the sites of induction of mucosal immune responses (Mestecky et al., 2003; Kiyono and Fukuyama,(More)
Mucosally ingested and inhaled antigens are taken up by membranous or microfold cells (M cells) in the follicle-associated epithelium of Peyer's patches or nasopharynx-associated lymphoid tissue. We established a novel M cell-specific monoclonal antibody (mAb NKM 16-2-4) as a carrier for M cell-targeted mucosal vaccine. mAb NKM 16-2-4 also reacted with the(More)
OBJECTIVE The study aimed to investigate the efficacy and adverse effects of sublingual immunotherapy (SLIT) of dust mite drops to allergic rhinitis with mite allergy. The compliance and satisfaction of SLIT were also assessed. METHOD One hundred and three patients of allergic rhinitis sensitive to dust mites were treated with SLIT for 6 months or more.(More)
Allergic diseases are chronic inflammatory conditions with specific immune and inflammatory mechanisms. Scientific interest in understanding the mechanisms and discovering novel agents for the prevention and treatment of allergic disease is increasing. Streptochlorin, a small compound derived from marine actinomycete possesses anti-angiogenic and anti-tumor(More)
A CMOS centric phase array radar architecture is proposed for long range detection with a high angular resolution and short range with a large field of view at once. And one channel transceiver is implemented in a 65nm CMOS technology and patch array antenna also fabricated on LTCC (Low Temperature Co-fired Ceramic) substrate for small form factor, low(More)
This paper aims to explore the nature of the research topics and methodologies used in the European Foundation for Quality Management (EFQM) business excellence model studies, as well as to suggest future research agendas. Results indicate that the majority of papers have paid too much attention to too few research topics (e.g., performance measurement) by(More)
PURPOSE This study evaluates offending allergens in patients with allergic rhinitis (AR) according to age that establish a minimal panel for skin prick test (SPT) allergens required to identify if a patient is sensitized. METHODS We retrospectively analyzed SPT results according to age to determine the minimum test battery panel necessary to screen at(More)