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We evaluated the involvement of collagen and their discoidin domain receptors (DDRs), DDR1 and DDR2, on the activation of human monocyte-derived dendritic cells (hDCs). DDR2 was markedly expressed on mature hDCs in comparison to immature ones. Collagen I enhanced the release of IL-12p40, TNF-α and IFN-γ by hDCs. Additionally, hDCs exhibited enhanced(More)
In a next generation network (NGN) service environment, telecommunication service will continue to change from technology-oriented service to service-oriented service and customers will demand value-added Differentiated Services. To succeed in this business environment, service providers must support the evolution of next generation services and change(More)
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