Dong Keon Yon

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There have been significant advances in our understanding of the immunology of allergic diseases in recent years. Most recent studies emphasize the importance of downregulation of Th1 and Th2 responses by regulatory T cells (Tregs), which is mediated by anti-inflammatory cytokines such as IL-10, rather than an imbalance of Th1 and Th2 responses.(1, 2) Many(More)
The Global Initiative for Asthma (GINA) guidelines do not specify a bronchodilator range for bronchodilator response (BDR) testing and simply recommend a salbutamol dose of 200 to 400 μg. We determined the oscillometric BDR results of children given low-dose (2 puffs, 200 μg) and standard-dose (4 puffs, 400 μg) salbutamol to compare the small airway(More)
Loss-of-function mutations in methyl-CpG-binding protein 2 (MECP2; MIM *300005) results in the Rett syndrome, whereas gain-of-function mutations are associated with the MECP2 duplication syndrome. We did research on a family with two brothers showing Xq28 duplication syndrome using various molecular cytogenetic techniques such as multiplex(More)
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