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Photodynamic therapy in the treatment of microbial infections: basic principles and perspective applications.

• Giulio Jori, Clara Fabris, +6 authors Gabrio Roncucci
• Lasers in surgery and medicine
• 2006

BACKGROUND AND OBJECTIVES Photodynamic therapy (PDT) appears to be endowed with several favorable features for the treatment of infections originated by microbial pathogens, including a broad… (More)

Approaches to selectivity in the Zn(II)-phthalocyanine-photosensitized inactivation of wild-type and antibiotic-resistant Staphylococcus aureus.

• Marina Soncin, Clara Fabris, +4 authors Giulio Jori
• Photochemical & photobiological sciences…
• 2002

A number of Zn(II)- phthalocyanines bearing peripheral substituents of cationic nature due to the presence of quaternarized anilinium or ammonium groups were shown to be efficient photoantimicrobial… (More)

Photophysical, photochemical and antibacterial photosensitizing properties of a novel octacationic Zn(II)-phthalocyanine.

• Anna Segalla, Claudio Darío Borsarelli, +6 authors E. U. B. Reddi
• Photochemical & photobiological sciences…
• 2002

A novel Zn(II)-phthalocyanine (1). peripherally substituted with four bis(N,N,N-trimethyl)amino-2-propyloxy groups prepared by chemical synthesis is shown to be an efficient photodynamic sensitizer… (More)

Zn(II)-phthalocyanines as phototherapeutic agents for cutaneous diseases. Photosensitization of fibroblasts and keratinocytes.

• Clara Fabris, Marina Soncin, +5 authors Giulio Jori
• Journal of photochemistry and photobiology. B…
• 2006

Two tetrasubstituted (RLP024 and RLP040) and one monosubstituted (MRLP101) Zn-phthalocyanines were readily accumulated by three skin-derived cell lines (HT-1080 transformed human fibroblasts, 3T3… (More)

Skin-photosensitizing properties of Zn(II)-2(3), 9(10), 16(17), 23(24)-tetrakis-(4-oxy-N-methylpiperidinyl) phthalocyanine topically administered to mice.

• Kawser Kassab, Clara Fabris, +5 authors Giulio Jori
• Journal of photochemistry and photobiology. B…
• 2000

A Zn-phthalocyanine derivative bearing four 4-oxy-N-methyl-piperidinyl peripheral substituents has been formulated in an azone-containing gel for topical administration and its potential as a… (More)

A novel tetracationic phthalocyanine as a potential skin phototherapeutic agent.

• Clara Fabris, Marina Soncin, +7 authors Giulio Jori
• Experimental dermatology
• 2005

An amphiphilic tetracationic derivative of Zn(II)-phthalocyanine (RLP068) was prepared by means of chemical synthesis and was showed to possess efficient photophysical and photosensitizing properties… (More)

Phthalocyanine-photosensitized inactivation of a pathogenic protozoan, Acanthamoeba palestinensis.

• Kawser Kassab, Donata Dei, Gabrio Roncucci, Giulio Jori, Olimpia Coppellotti
• Photochemical & photobiological sciences…
• 2003

Incubation of Acanthamoeba palestinensis cells with a tetracationic phthalocyanine (RLP068) at concentrations ranging between 0.2 and 1.0 microM, caused a ready uptake of the photosensitizer with… (More)

A novel 10B-enriched carboranyl-containing phthalocyanine as a radio- and photo-sensitising agent for boron neutron capture therapy and photodynamic therapy of tumours: in vitro and in vivo studies.

• Elisabetta Friso, Gabrio Roncucci, +11 authors Giulio Jori
• Photochemical & photobiological sciences…
• 2006

The synthesis of a Zn(ii)-phthalocyanine derivative bearing four 10B-enriched o-carboranyl units (10B-ZnB4Pc) and its natural isotopic abundance analogue (ZnB4Pc) in the peripheral positions of the… (More)

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