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BACKGROUND Nonsteroidal anti-inflammatory drugs (NSAIDs) may protect against Alzheimer disease (AD), but observational studies and trials have offered contradictory results. Prior studies have also been relatively short and small. We examined the effects on AD risk of NSAID use for >5 years and of NSAIDs that suppress formation of A beta (1-42) amyloid in a(More)
Event-related potentials (ERPs) were recorded to both predictive (consonant-vowel-consonant) and feedback (picture) stimuli as subjects learned associations between these stimuli. Tbe eonsonant-vowel-consonants (CVCs) were selected for lack of emotional content while the pictures (PICs) varied in emotional value (Learning Group; N = 20). A second group of(More)
OBJECTIVE The authors examined the self-reported presence and treatment of current depressive disorder, posttraumatic stress disorder (PTSD), and alcohol-related disorder in a group of outpatient veterans. METHOD Data were obtained from the Veterans Health Study, a longitudinal investigation of male veterans' health. A representative sample of 2,160(More)
This is a study of the encoding and decoding of emotional facial expressions by people diagnosed as schizophrenic. The results of most previous investigations have shown that schizophrenics are worse than other psychiatric and normal comparison groups at adopting and recognizing facial expressions of emotion. This study is the first in which both abilities(More)
Role functioning and its limitations due to one's health is an important aspect of health-related quality of life (HRQoL). The Medical Outcomes Study (MOS) SF-36 includes 2 role functioning scales: role limitations due to physical health problems (RP) or emotional problems (RE). Although they capture important concepts of HRQoL, these 2 scales have some(More)
The Medicare Health Outcomes Survey (HOS) uses the Medical Outcomes Study (MOS) SF-36 among beneficiaries enrolled in Medicare managed care programs, whereas the Department of Veterans Affairs (VA), Veterans Health Administration (VHA) has administered the Veterans version of the SF-36 for quality management purposes. The Veterans version is comparable to(More)
BACKGROUND Skin cancer is the most common cancer in the United States. Increasing evidence suggests that screening for malignant melanoma is effective, but its cost-effectiveness has not been determined. OBJECTIVE We attempted to determine the effectiveness and costs of a visual screen to diagnose malignant melanoma in high-risk persons. METHODS We(More)
BACKGROUND Hypertension, hyperlipidemia, diabetes, and obesity in middle adulthood each elevate the long-term risk of cardiovascular disease (CVD). The prevalence of these conditions among women veterans is incompletely described. OBJECTIVE To describe the prevalence of CVD risk factors among women veterans in middle adulthood. DESIGN Serial(More)
BackgroundThe mood stabilisers lithium and valproate might plausibly have differing associations with mortality because of differing effects on mental health and various physiological indicators.AimsTo assess associations between lithium, valproate and non-suicide mortality.MethodIntention-to-treat, propensity score-matched cohort study.ResultsLithium was(More)
OBJECTIVE To evaluate temporal trends in rates of initial lower extremity amputation (ILEA) among patients with diabetes in the Veterans Health Administration (VHA). RESEARCH DESIGN AND METHODS Retrospective administrative data analysis of VHA clinic users with diabetes in fiscal years (FY) 2000 to 2004 (1 October 1999-30 September 2004). We calculated(More)