Learn More
OBJECTIVE To compare the course of continuously measured mixed and central venous O(2) saturations in high-risk patients and to evaluate the impact of various factors that might interfere with reflection spectrophotometry. DESIGN AND SETTING Prospective, descriptive study in the interdisciplinary ICU of a university hospital. PATIENTS 32 critically ill(More)
Because central venous O2 saturation (superior vena cava, ScvO2) can be monitored with less patient risk than mixed venous O2 saturation (pulmonary artery, SvO2), we examined the correlations between SvO2 and ScvO2 over a broad range of cardiorespiratory conditions, including hypoxia, hemorrhage, and resuscitation in anesthetized dogs. The correlation(More)
OBJECTIVE To assess the effects of epinephrine on splanchnic perfusion and splanchnic oxygen uptake in patients with septic shock. DESIGN Prospective, controlled trial. SETTING University hospital intensive care unit (ICU). PATIENTS Eight patients with septic shock, according to the criteria of the 1992 American College of Chest Physicians/Society of(More)
OBJECTIVE We examined the effects of arginine vasopressin, when substituted for norepinephrine as a vasopressor in septic shock, on global and hepatosplanchnic hemodynamic and oxygen transport variables. DESIGN Experimental study. SETTING Intensive care unit. SUBJECTS Twelve septic shock patients. INTERVENTIONS Norepinephrine was replaced by(More)
OBJECTIVE To assess the effects of dopexamine on splanchnic blood flow and splanchnic oxygen uptake in septic patients. DESIGN A prospective, controlled trial. SETTING A ten-bed intensive care unit (ICU) in a university hospital. PATIENTS Twelve patients with severe sepsis (according to the criteria of the 1992 American College of Chest(More)
PURPOSE The purpose of this study was to analyze three different variables of cardiac preload; central venous pressure (CVP), pulmonary artery occlusion pressure (PAOP), and intrathoracic blood volume index (ITBVI) that served as the best indicator of cardiac function, that is, cardiac index (C1) or stroke index (SI). MATERIALS AND METHODS This was a(More)
OBJECTIVE To assess the effects of low-dose dopamine on splanchnic blood flow and splanchnic oxygen uptake in patients with septic shock. DESIGN Prospective, controlled trial. SETTING University hospital intensive care unit. PATIENTS 11 patients with septic shock, diagnosed according the criteria of the 1992 American College of Chest(More)
The proliferation of alarms on equipment in ICUs contributes to a level of noise that can disturb both patient and staff. To determine whether these alarms are identifiable by sound alone to our ICU staff, we recorded 33 audio signals commonly heard on the ward, 10 of which we defined as critical alarms. One hundred subjects (25 physicians, 41 nurses, and(More)
OBJECTIVE To assess global and splanchnic blood flow and oxygen transport in patients with sepsis with and without norepinephrine treatment. DESIGN Prospective, clinical study. SETTING University hospital intensive care unit. PATIENTS A convenience sample of 15 septic shock patients treated with norepinephrine and 13 patients with severe sepsis who(More)
OBJECTIVE To test whether dopexamine hydrochloride, by its beta 2-adrenoreceptor and dopaminergic 1 (DA1) and dopaminergic 2 (DA2) agonistic properties, can improve oxygen consumption (VO2) in hyperdynamic patients with septic shock. DESIGN Prospective, single-cohort study. SETTING ICU, university hospital. PATIENTS Twenty-nine postoperative,(More)