Donald L. Bitzer

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A decoding algorithm is tested that mechanistically models the progressive alignments that arise as the mRNA moves past the rRNA tail during translation elongation. Each of these alignments provides an opportunity for hybridization between the single-stranded, 3'-terminal nucleotides of the 16S rRNA and the spatially accessible window of mRNA sequence, from(More)
The option of obtaining education over networks is quickly becoming a reality for all those that have access to Internet and WorldWide Web (WWW). However, at present network-based education (NBE) over WWW, and over Internet in general, faces a number of pitfalls. The problems range from inadequate end-user quality of service (QoS), to inadequate materials,(More)
The q-matrix method, a new method for data mining and knowledge discovery, is compared with factor analysis and cluster analysis in analyzing fourteen experimental data sets. This method creates a matrix-based model that extracts latent relationships among observed binary variables. Results show that the q-matrix method offers several advantages over factor(More)
Lip synchronization is the determination of the motion of the mouth and tongue during speech. It can be deduced from the speech signal without phonemic analysis, and irrespective of the content of the speech. Our method is based on the observation that the position of the mouth over a short interval of time can be correlated with the basic shape of the(More)
By analyzing the absolute value of the Fourier transform of a speaker's voice signal we can predict the position of the mouth for English vowel sounds. This is without the use of text, speech recognition or mechanical or other sensing devices attached to the speaker's mouth. This capability can reduce the time required for mouth animation considerably. We(More)
Our research explores the feasibility of using communication theory, error control (EC) coding theory specifically, for quantitatively modeling the protein translation initiation mechanism. The messenger RNA (mRNA) of Escherichia coli K-12 is modeled as a noisy (errored), encoded signal and the ribosome as a minimum Hamming distance decoder, where the 16S(More)
Error control schemes are becoming increasingly important as the needs increase for very high rates of data transmission over inherently noisy channels (e.g. satellite and spread-spectrum communication). Forward error-correction is one means of improving channel performance, but at high data transmission rates very efficient decoder implementations are(More)