Donald Burton Myers

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Glutaraldehyde fixation and osmication of rat sciatic nerve and human sural nerve did not appreciably alter the apparent weight of collagen in nerve fasciculi as determined by hydroxyproline analysis of hydrolysed samples. The collagen content of autopsied peripheral nerve is unaltered at least up to 24 h after death. The mean endoneurial weight of collagen(More)
A new electronic dynanometer was developed and used to determine hand grip function in patients with rheumatoid arthritis. Triplicate pressure-time recordings of grip for each hand were used to calculate maximum grip strength, time required to reach 95% maximum grip strength (t95), total work and maximum power output. Measurements were done on 30 women aged(More)
This study investigated the immunohistochemical distribution of collagen type I and laminin during remodeling of the uterine extracellular matrix in response to embryo implantation in the rat. Collagen type I was found to be virtually absent around the embryo on the evening of day 5 of pregnancy. On days 6 to 8 of pregnancy the areas of primary and(More)
Low molecular weight (Mr 200-1500) N-formylated peptides that stimulate many leucocyte functions, including chemotaxis and lysosomal enzyme release, have previously been isolated from Escherichia coli cultures. We have used high-performance liquid chromatography and bioassay techniques to study production of such peptides by intestinal bacteria in vitro and(More)
Uteri of pregnant rats on Days 6, 7 and 8 of pregnancy were studied to determine the histochemical distribution of collagen types III and V and the incorporation of [3H]glycine into fibrillar collagens during the period of embryonic implantation. Types III and V had a similar distribution in the non-decidual stromal region and muscle layers in implantation(More)
A quantitative analysis of ulnar nerve collagen in the arm and forearm was undertaken in nine subjects. While endoneurial collagen was found to be significantly increased within the cubital tunnel, extrafascicular collagen did not increase at the elbow except in two nerves showing fusiform enlargements. Renaut bodies increased in frequency at sites of high(More)
Collagen content of rat sciatic nerve was measured 10 weeks after either nerve transection or nerve crush. Nerve transection led to a significant increase in fascicular collagen in nerve segments 2.5 mm proximal and distal to the injury site. Remote from the transection, fascicular collagen was also significantly increased, this effect being most marked(More)