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The 5.67-megabase genome of the plant pathogen Agrobacterium tumefaciens C58 consists of a circular chromosome, a linear chromosome, and two plasmids. Extensive orthology and nucleotide colinearity between the genomes of A. tumefaciens and the plant symbiont Sinorhizobium meliloti suggest a recent evolutionary divergence. Their similarities include(More)
BACKGROUND Francisella tularensis subspecies tularensis and holarctica are pathogenic to humans, whereas the two other subspecies, novicida and mediasiatica, rarely cause disease. To uncover the factors that allow subspecies tularensis and holarctica to be pathogenic to humans, we compared their genome sequences with the genome sequence of Francisella(More)
permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Pathogenicity in Francisella tularensis subspecies <p>.Sequencing of the non-pathogenic <it>Francisella tularensis </it>sub-species novicida U112, and comparison with two pathogenic sub-species, provides insights into the evolution of(More)
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