Don Stehouwer

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High fasting plasma homocysteine levels (> 12 to 15 mumol/L) are commonly encountered in clinical practice and are associated with increased risk of atherothrombotic disease. Treatment with folic acid (1 to 5 mg/day) is inexpensive and effective in normalising plasma homocysteine levels. High plasma homocysteine levels after methionine loading (> 40 to 50(More)
O besity, in particular central obesity, is characterized by a state of chronic low-grade inflammation (LGI) that has been linked to the increased risk of insulin resistance and type 2 diabetes mellitus (T2DM). Increasing evidence indicates that the adipose tissue is an active endocrine organ that produces several biological active mediators of LGI, which(More)
Oral estrogen administration decreases plasma levels of tissue-type plasminogen activator (tPA), which may be explained by a decrease in endothelial tPA synthesis, an increase in its hepatic clearance, or both. In the present study, we determined (1) differences between oral (ie, via the liver) ethinyl estradiol and transdermal (ie, systemic) 17b-estradiol(More)
of Dissertation Presented to the Graduate School of the University of Florida in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy THE TRANSFORMATIONAL COMPLEXITY OF ACYCLIC NETWORKS OF NEURONS By Venkatakrishnan Ramaswamy May 2011 Chair: Arunava Banerjee Major: Computer Engineering Neurons are cells in the brain thought to be(More)
DIABETES CARE, VOLUME 23, NUMBER 1, JANUARY 2000 The American Diabetes Association (ADA) recently introduced new diagnostic criteria for the diagnosis of diabetes (1). In contrast to the 1985 Wo r l d Health Organization (WHO) criteria (2), the ADA criteria are based on fasting plasma glucose (FPG) levels only, and consequently an oral glucose tolerance(More)
Abstract—Carotid intima-media thickness (CIMT) is a marker of cardiovascular risk. It is unclear whether measurement of mean common CIMT improves 10-year risk prediction of first-time myocardial infarction or stroke in individuals with elevated blood pressure. We performed an analysis among individuals with elevated blood pressure (ie, a systolic blood(More)
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