Don A. Kennard

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Recombinant human PH20 hyaluronidase (rHuPH20) is used to facilitate dispersion of subcutaneously delivered fluids and drugs. This report summarizes rHuPH20 immunogenicity findings from clinical trials where rHuPH20 was co-administered with SC human immunoglobulin, trastuzumab, rituximab, or insulin. Plasma samples were obtained from evaluable subjects(More)
1 Halozyme Therapeutics, Inc., 11388 Sorrento Valley Road, San Diego, California 92121, USA. 2 Baxter Bioscience, Deerfield, Illinois, USA. 3 Baxter Bioscience, Vienna, Austria. 4 Baxter Healthcare Corporation, Deerfield, Illinois, USA. 5 To whom correspondence should be addressed. (e-mail: The AAPS Journal, Vol. 17, No. 6, November(More)
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