Dominique Mouchiroud

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Expression pattern and, surprisingly, gene length shape codon usage in Caenorhabditis, Drosophila, and Arabidopsis.

Laurent Duret, Dominique Mouchiroud
Proceedings of the National Academy of Sciences…
1999

We measured the expression pattern and analyzed codon usage in 8,133, 1,550, and 2,917 genes, respectively, from Caenorhabditis elegans, Drosophila melanogaster, and Arabidopsis thaliana. In those… (More)

CpGProD: identifying CpG islands associated with transcription start sites in large genomic mammalian sequences

Loïc Ponger, Dominique Mouchiroud
Bioinformatics
2002

RESULTS CpGProD is an application for identifying mammalian promoter regions associated with CpG islands in large genomic sequences. Although it is strictly dedicated to this particular promoter… (More)

Sensitivity of the relative-rate test to taxonomic sampling.

Micah Robinson, Manolo Gouy, Christian Gautier, Dominique Mouchiroud
Molecular biology and evolution
1998

Relative-rate tests may be used to compare substitution rates between more than two sequences, which yields two main questions: What influence does the number of sequences have on relative-rate tests… (More)

Determinants of substitution rates in mammalian genes: expression pattern affects selection intensity but not mutation rate.

Laurent Duret, Dominique Mouchiroud
Molecular biology and evolution
2000

To determine whether gene expression patterns affect mutation rates and/or selection intensity in mammalian genes, we studied the relationships between substitution rates and tissue distribution of… (More)

Does recombination improve selection on codon usage? Lessons from nematode and fly complete genomes.

Gabriel A. B. Marais, Dominique Mouchiroud, Laurent Duret
Proceedings of the National Academy of Sciences…
2001

Understanding the factors responsible for variations in mutation patterns and selection efficacy along chromosomes is a prerequisite for deciphering genome sequences. Population genetics models… (More)

Vanishing GC-rich isochores in mammalian genomes.

Laurent Duret, Marie Sémon, Gwenaël Piganeau, Dominique Mouchiroud, Nicolas Galtier
Genetics
2002

To understand the origin and evolution of isochores-the peculiar spatial distribution of GC content within mammalian genomes-we analyzed the synonymous substitution pattern in coding sequences from… (More)

GC-content evolution in mammalian genomes: the biased gene conversion hypothesis.

Nicolas Galtier, Gwenaël Piganeau, Dominique Mouchiroud, Laurent Duret
Genetics
2001

BASE composition is spatially structured in mammaisochores may simply reflect variable mutation processes among genomic regions, consistent with the neutral lian genomes. From sodium chloride… (More)

Statistical analysis of vertebrate sequences reveals that long genes are scarce in GC-rich isochores

Laurent Duret, Dominique Mouchiroud, Christian Gautier
Journal of Molecular Evolution
1995

We compared the exon/intron organization of vertebrate genes belonging to different isochore classes, as predicted by their GC content at third codon position. Two main features have emerged from the… (More)

A Gradual Process of Recombination Restriction in the Evolutionary History of the Sex Chromosomes in Dioecious Plants

Michael Nicolas, Gabriel A.B. Marais, +7 authors Françoise Monéger
PLoS biology
2005

To help understand the evolution of suppressed recombination between sex chromosomes, and its consequences for evolution of the sequences of Y-linked genes, we have studied four X-Y gene pairs,… (More)

Molecular phylogeny of rodents, with special emphasis on murids: evidence from nuclear gene LCAT.

Micah Robinson, François M. Catzéflis, Jérǒme Briolay, Dominique Mouchiroud
Molecular phylogenetics and evolution
1997

Phylogenetic relationships among 19 extant species of rodents, with special emphasis on rats, mice, and allied Muroidea, were studied using sequences of the nuclear protein-coding gene LCAT… (More)

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