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Serial estimations of plasma carcinoembryonic antigen (C.E.A.) levels have been carried out in 220 patients with colorectal carcinomas who had potentially and apparently curative surgery. In a two-year follow-up period 53 patients developed recurrences or metastases. In 36 of these patients sustained rises in plasma C.E.A. titres occurred synchronously with(More)
DURING the past decade, there has been a renewed wave of interest in tumour immunology and in particular in the search for components or functions of cancer cells not shared by their normal counterparts. One goal has been to elucidate if tumours do or do not contain "tumour-specific or associated anti-gens ". Most of the investigations have been effected(More)
Our studies have confirmed that raised plasma levels of carcinoembryonic antigen (C.E.A.) occur with many but not all malignant tumours, particularly those of the gastrointestinal tract, breast, and bronchus. However, the incidence of raised values may reach 30% in diseases associated with inflammation or regeneration or both. Consequently, it cannot serve(More)