Dominique H Criblez

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BACKGROUND/AIMS Herbal agents are popular and perceived as safe because they are supposedly 'natural'. We report 10 cases of toxic hepatitis implicating Herbalife products. METHODS To determine the prevalence and outcome of hepatotoxicity due to Herbalife products. A questionnaire was sent to all public Swiss hospitals. Reported cases were subjected to(More)
Health regulatory approval of the 1.5 microg/kg body weight dose of pegylated interferon (PEG-I) alpha-2b in combination with ribavirin for the treatment of chronic hepatitis C was based on a study using PEG-I alpha-2b at doses of only 0.5 and 1.5 microg/kg body weight (BW), in spite of the previously shown flat dose-response curve at doses of > or =1.0(More)
PURPOSE This study was designed to evaluate the accuracy of four different fecal markers in discriminating between irritable bowel syndrome, inflammatory bowel disease, and other forms of colitis and to examine the feasibility of collecting fecal samples in outpatients. METHODS We prospectively included 20 patients with irritable bowel syndrome, 36 with(More)
Together with three of our own observations of intramural rupture (IRO) or hematoma (IHO) of the esophagus, we have analyzed 91 case reports from the literature. Precipitating factors were identified in 63% of all patients. Most frequently potentially traumatic events such as vomiting (22%) or instrumentation (17%) preceded IRO/IHO. In 21% there were(More)
G f i Question: A 17-year-old, previously healthy male patient was admitted to the emergency ward because of acute onset of severe epigastric pain and nausea, without vomiting. He denied any drug or alcohol intake. On physical examination, his temperature was normal, and he was not jaundiced. Tenderness of the upper abdomen and scarce bowel sounds were(More)
A 68-year-old patient presenting with non-specific abdominal symptoms was diagnosed as having multiple gastric carcinoid tumours with H. pylori-positive chronic atrophic gastritis and hypergastrinaemia. No metastases were found. As he was inoperable due to comorbidity, conservative management was instituted. The patient was followed for 6 years without(More)
  • D H Criblez
  • 1998
A 89-yr-old woman presenting with dysphagia due to an obstructing adenocarcinoma of the distal esophagus was additionally diagnosed to have an upside-down stomach creating a sharp angulation at the esophagogastric junction. Gastric anatomy had to be restored before palliative stent insertion. As the patient was judged unfit for surgery, the stomach was(More)
Acute abdominal pain remains a diagnostic challenge even today. Although computer-assisted diagnostic aids have been designed, these are not yet well established in clinical practice. Thus when facing this problem most physicians rely on experience and sound knowledge of the broad etiological spectrum of acute abdominal pain. In the first section of this(More)
Patient history, physical examination and basic laboratory tests often allow the clinician to suspect one of the numerous aetiologies of diarrhea and consequently establish a rapid diagnosis. Otherwise, the workup of diarrhea, especially when chronic, may represent a challenge. In this brief tutorial article a practical algorithm is proposed to guide the(More)
Gastrointestinal endoscopy offers a variety of methods for palliative treatment of tumor symptoms, most importantly self-expanding metal stents. Stent insertion achieves effective recanalisation of malignant stenoses in various locations of the gastrointestinal tract. This tutorial paper briefly reviews some of these methods. Special consideration is given(More)