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- G M Kemp, Peter Rose, +6 authors J Glick
- Journal of clinical oncology : official journal…
- 1996
PURPOSE
Serious cumulative toxicity is a well-recognized consequence of chemotherapy. Amifostine, an organic thiophosphate, has demonstrated the ability to protect selectively a broad range of… (More)
- Philippe Irigaray, J A Newby, +5 authors Dominique Belpomme
- Biomedicine & pharmacotherapy = Biomedecine…
- 2007
The increasing incidence of a variety of cancers after the Second World War confronts scientists with the question of their origin. In Western countries, expansion and ageing of the population as… (More)
- Dominique Belpomme, Philippe Irigaray, +4 authors Annie Jeanne Sasco
- Environmental research
- 2007
We have recently proposed that lifestyle-related factors, screening and aging cannot fully account for the present overall growing incidence of cancer. In order to propose the concept that in… (More)
- Philippe Irigaray, J A Newby, Stéphanie Lacomme, Dominique Belpomme
- Biomedicine & pharmacotherapy = Biomedecine…
- 2007
The classical view according to which overweight/obesity is related to cancer considers adipose tissue as an active and metabolic "organ", acting through endocrine, autocrine and paracrine processes.… (More)
- Barbara Chiavarina, Marie-Julie Nokin, +10 authors Akeila Bellahcène
- Oncotarget
- 2014
Metabolic syndrome and type 2 diabetes are associated with increased risk of breast cancer development and progression. Methylglyoxal (MG), a glycolysis by-product, is generated through a… (More)
- Marie-Julie Nokin, Florence Durieux, +22 authors Akeila Bellahcène
- eLife
- 2016
Metabolic reprogramming toward aerobic glycolysis unavoidably induces methylglyoxal (MG) formation in cancer cells. MG mediates the glycation of proteins to form advanced glycation end products… (More)
- Dominique Belpomme, Sophie Gauthier, +9 authors F. Sturtz
- Annals of oncology : official journal of the…
- 2000
BACKGROUND
Verapamil (VER), a potent calcium channel blocker, has been found to overcome P-gp-mediated multi-drug resistance (MDR) and to increase sensitivity to cytotoxic anticancer drugs in… (More)
- Dominique Belpomme, Philippe Irigaray
- Prostate cancer
- 2011
Prostate cancer incidence is steadily increasing in many developed countries. Because insular populations present unique ethnic, geographical, and environmental characteristics, we analyzed the… (More)
- Bertrand Dautzenberg, Claude Chastang, +7 authors R. A. Guerin
- Cancer
- 1995
BACKGROUND
The effect of adjuvant chemotherapy after resection of nonsmall cell lung cancer (NSCLC) remains an unresolved question.
METHODS
From October, 1982, to November, 1986, 267 patients with… (More)
- J. L. Misset, Mario di Palma, +11 authors Georges Mathé
- Journal of clinical oncology : official journal…
- 1996
PURPOSE
To determine the long-term impact on disease-free survival (DFS) and overall survival (OS) of adjuvant anthracycline-based chemotherapy, when prospectively compared by random allocation with… (More)