Dominique Belpomme

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Amifostine pretreatment for protection against cyclophosphamide-induced and cisplatin-induced toxicities: results of a randomized control trial in patients with advanced ovarian cancer.

Gary Kemp, Paulina Rose, +6 authors John Glick
Journal of clinical oncology : official journal…
1996

PURPOSE Serious cumulative toxicity is a well-recognized consequence of chemotherapy. Amifostine, an organic thiophosphate, has demonstrated the ability to protect selectively a broad range of… (More)

The multitude and diversity of environmental carcinogens.

Dominique Belpomme, Philippe Irigaray, +4 authors Annie Jeanne Sasco
Environmental research
2007

We have recently proposed that lifestyle-related factors, screening and aging cannot fully account for the present overall growing incidence of cancer. In order to propose the concept that in… (More)

Philippe Irigaray, J A Newby, +5 authors Dominique Belpomme
Biomedicine & pharmacotherapy = Biomedecine…
2007

The increasing incidence of a variety of cancers after the Second World War confronts scientists with the question of their origin. In Western countries, expansion and ageing of the population as… (More)

Basic properties and molecular mechanisms of exogenous chemical carcinogens.

Exogenous chemical carcinogenesis is an extremely complex multifactorial process during which gene-environment interactions involving chronic exposure to exogenous chemical carcinogens (ECCs) and… (More)

Overweight/obesity and cancer genesis: more than a biological link.

Philippe Irigaray, J A Newby, Stéphanie Lacomme, Dominique Belpomme
Biomedicine & pharmacotherapy = Biomedecine…
2007

The classical view according to which overweight/obesity is related to cancer considers adipose tissue as an active and metabolic "organ", acting through endocrine, autocrine and paracrine processes.… (More)

Verapamil increases the survival of patients with anthracycline-resistant metastatic breast carcinoma.

Dominique Belpomme, Sophie Gauthier, +9 authors F. Sturtz
Annals of oncology : official journal of the…
2000

BACKGROUND Verapamil (VER), a potent calcium channel blocker, has been found to overcome P-gp-mediated multi-drug resistance (MDR) and to increase sensitivity to cytotoxic anticancer drugs in… (More)

Phase II clinical trial with vindesine for remission induction in acute leukemia, blastic crisis of chronic myeloid leukemia, lymphosarcoma, and hodgkin's disease: absence of cross-resistance with…

Georges Mathé, J. L. Misset, +10 authors Leonardo De Luca
Cancer treatment reports
1978

Vindesine, an analog of vinblastine and vincristine, has been submitted to a phase II trial, the results of which are judged in terms of remission induction. A high proportion of remissions were… (More)

Triple negative tumors accumulate significantly less methylglyoxal specific adducts than other human breast cancer subtypes

Barbara Chiavarina, Marie-Julie Nokin, +10 authors Akeila Bellahcéne
Oncotarget
2014

Metabolic syndrome and type 2 diabetes are associated with increased risk of breast cancer development and progression. Methylglyoxal (MG), a glycolysis by-product, is generated through a… (More)

Adjuvant treatment of node-positive breast cancer with cyclophosphamide, doxorubicin, fluorouracil, and vincristine versus cyclophosphamide, methotrexate, and fluorouracil: final report after a…

J. L. Misset, Mario di Palma, +11 authors Georges Mathé
Journal of clinical oncology : official journal…
1996

PURPOSE To determine the long-term impact on disease-free survival (DFS) and overall survival (OS) of adjuvant anthracycline-based chemotherapy, when prospectively compared by random allocation with… (More)

T and B lymphocyte markers on the neoplastic cell of 20 patients with acute and 10 patients with chronic lymphoid leukemia.

Dominique Belpomme, D K Dantchev, +6 authors Georges Mathé
Biomedicine / [publiee pour l'A.A.I.C.I.G.]
1974

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