Christopher J Bockisch26
Sarah Marti20
26Christopher J Bockisch
20Sarah Marti
12Alexander A Tarnutzer
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The semi-circular canals and the otolith organs both contribute to gaze stabilization during head movement. We investigated how these sensory signals interact when they provide conflicting information about head orientation in space. Human subjects were reoriented 90 degrees in pitch or roll during long-duration, constant-velocity rotation about the(More)
BACKGROUND The rotational vestibulo-ocular reflex (rVOR) generates compensatory eye movements in response to rotational head accelerations. The velocity-storage mechanism (VSM), which is controlled by the vestibulo-cerebellar nodulus and uvula, determines the rVOR time constant. In healthy subjects, it has been suggested that self-motion perception in(More)
PURPOSE Most studies on blink-induced eye movements have been restricted to rotations about the horizontal and vertical axes. By additionally measuring rotation about the torsional axis, the authors investigated whether the three-dimensional rotation of the eye during the early phase of eyelid closure could be assigned to the action of a single extraocular(More)
We compared the variability of the subjective visual vertical (SVV) and static ocular counterroll (OCR), and hypothesized a correlation between the measurements because of their shared macular input. SVV and OCR were measured simultaneously in various whole-body roll positions [upright, 45 degrees right-ear down (RED), and 75 degrees RED] in six subjects.(More)
INTRODUCTION Unrealistic optimism refers to the pervasive tendency of healthy individuals to underestimate their likelihood of future misfortune, including illness. The phenomenon shares a qualitative resemblance with anosognosia, a neurological disorder characterized by a deficient appreciation of manifest current illness or impairment. Unrealistic(More)
Downbeat nystagmus is a frequent ocular motor sign in patients with lesions of the vestibulocerebellum. The upward drift in downbeat nystagmus is a combination of a gaze-evoked drift, due to an impaired vertical neural integrator, and a velocity bias. Using a three-dimensional turntable, we analyzed the influence of gravity on these two mechanisms. Patients(More)
BACKGROUND When roll-tilted, the subjective visual vertical (SVV) deviates up to 40 degrees from earth-vertical and trial-to-trial variability increases with head roll. Imperfections in the central processing of visual information were postulated to explain these roll-angle dependent errors. For experimental conditions devoid of visual input, e.g.(More)
Vestibular velocity storage enhances the efficacy of the angular vestibulo-ocular reflex (VOR) during relatively low-frequency head rotations. This function is modulated by GABA-mediated inhibitory cerebellar projections. Velocity storage also exists in perceptual pathway and has similar functional principles as VOR. However, it is not known whether the(More)
OBJECTIVE To identify under-diagnosed neuro-otological disorders and to evaluate whether under-diagnosing depends on the age of the patient. MATERIALS AND METHODS Retrospective analysis of medical charts from 951 consecutive patients (685 under and 266 above the age of 65 years) who entered diagnostic procedures at the Interdisciplinary Center for Vertigo(More)
Experimental animal models have suggested that the modulation of the amplitude and direction of vestibular reflexes are important functions of the vestibulocerebellum and contribute to the control of gaze and balance. These critical vestibular functions have been infrequently quantified in human cerebellar disease. In 13 subjects with ataxia telangiectasia(More)