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Characterization of a Protein Phosphatase 2A Holoenzyme That Dephosphorylates the Clathrin Adaptors AP-1 and AP-2*
The AP-2 complex is a key factor in the formation of endocytic clathrin-coated vesicles (CCVs). AP-2 sorts and packages cargo membrane proteins into CCVs, binds the coat protein clathrin, andExpand
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The de-ubiquitylating enzyme DUBA is essential for spermatogenesis in Drosophila
De-ubiquitylating enzymes (DUBs) reverse protein ubiquitylation and thereby control essential cellular functions. Screening for a DUB that counteracts caspase ubiquitylation to regulate cellExpand
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Charakterisierung der AP2 dephosphorylierendenPhosphatase PP2A und Identifikation vonB55 alpha Bindungspartnern
Der Adaptorprotein-Komplex 2 (AP2) ist ein Schlusselfaktor bei der Bildung von Clathrin-coated vesicles (CCVs), die im Rahmen der Endozytose an der Plasmamembran gebildet werden. DieExpand