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BACKGROUND AND OBJECTIVES Mesenchymal stem/progenitor cells (MSCs) are multipotent progenitors that differentiate into such lineages as bone, fat, cartilage and stromal cells that support… Expand
Umbilical cord blood (UCB) and bone marrow (BM)-derived stem and progenitor cells possess two characteristics required for successful tissue regeneration: extensive proliferative capacity and the… Expand
Basic and clinical studies have shown that bone marrow cell therapy can improve cardiac function following infarction. In experimental animals, reported stem cell-mediated changes range from no… Expand
Summary Murine models of bone marrow transplantation show that pre‐conditioning regimens affect the integrity of the bone marrow endothelium and that the repair of this vascular niche is an essential… Expand
Background:Amitochondrialspecificdeacetylase,Sirtuin-3hasbeenreportedtoregulateoxidative phosphorylation, the activity of Cyclophilin D (a key component of the mitochondrial permeability transition… Expand