Dominic J. Lee

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The twist, rise, slide, shift, tilt and roll between adjoining base pairs in DNA depend on the identity of the bases. The resulting dependence of the double helix conformation on the nucleotide sequence is important for DNA recognition by proteins, packaging and maintenance of genetic material, and other interactions involving DNA. This dependence, however,(More)
This study revisits the classical x-ray diffraction patterns from hydrated, noncrystalline fibers originally used to establish the helical structure of DNA. We argue that changes in these diffraction patterns with DNA packing density reveal strong azimuthally dependent interactions between adjacent molecules up to approximately 40 A interaxial or(More)
A renormalization-group scheme is developed for the 3-dimensional O(2N)-symmetric Ginzburg-Landau-Wilson model, which is consistent with the use of a 1/N expansion as a systematic method of approximation. It is motivated by an application to the critical properties of superconductors, reported in a separate paper. Within this scheme, the infrared stable(More)
The theory of X-ray diffraction from ideal, rigid helices allowed Watson and Crick to unravel the DNA structure, thereby elucidating functions encoded in it. Yet, as we know now, the DNA double helix is neither ideal nor rigid. Its structure varies with the base pair sequence. Its flexibility leads to thermal fluctuations and allows molecules to adapt their(More)
We extend to finite temperature the time-dependent effective theory for the Gold-stone field (the phase of the pair field) θ which is appropriate for a superfluid containing one species of fermions with s-wave interactions, described by the BCS Lagrangian. We show that, when Landau damping is neglected, the effective theory can be written as a local(More)
We extend to finite temperature the time-dependent effective theory for the Goldstone field (the phase of the pair field) θ which is appropriate for superconductors containing one species of charge carrier, described by the BCS Lagrangian. We show that, when Landau damping is neglected, the effective theory can be written as a local time-dependent(More)
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