Dolores M Guerin

  • Citations Per Year
Learn More
Summary: This study was designed to determine the critical difference between rat milk and rat chow with respect to their effects on jejunal sucrase activity during the fourth postnatal wk. Rats were weaned onto special diets on postnatal day 17, and jejunal sucrase was assayed on day 28. A pelleted diet containing lactose as sole carbohydrate did not cause(More)
The binding to human rhinovirus 14 of a series of eight antiviral agents that inhibit picornaviral uncoating after entry into host cells has been characterized crystallographically. All of these bind into the same hydrophobic pocket within the viral protein VP1 beta-barrel structure, although the orientation and position of each compound within the pocket(More)
This study was performed to test the hypothesis that expression of heat shock proteins (HSPs) exhibits a spatially selective response within intact human skin following in vivo exposure to thermal stress. This response is believed to protect cells and tissues from further damage. Using Western blotting and immunohistochemistry, we studied the expression of(More)
Angiosarcoma has frequently been described arising within chronic lymphoedema of the upper limb following mastectomy and radiotherapy for carcinoma of the breast. We report a case of angiosarcoma arising in a lymphoedematous leg that had been subjected to radiotherapy 20 years previously for Hodgkin's disease. The diagnosis was expedited once the patient(More)
A diurnal rhythm of jejunal sucrase activity has been shown previously to make its developmental appearance in the rat at the time of weaning (Day 22). In this study we found that the rhythm was not present on Day 23 if the onset of feeding was not coordinated with the onset of darkness. Conversely, the sucrase rhythm appeared precociously (Day 19) in pups(More)
Combining a rotating polarizer with an image-processing technique permits the visual identification of the linearly polarized beams present in a field of view. The resulting images show the polarizations in a scene, regardless of the orientation of their electric-field vectors, with simultaneous suppression of unpolarized light.