Doja S. Sarieddine

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Rheumatoid arthritis is a destructive autoimmune disease that affects 3% of the adult population. It is characterized by the formation of both articular and extra-articular lesions with predilection for small joints. There are ubiquitous reports on the head and neck manifestations of RA with emphasis on the larynx. The laryngeal presenting features of this(More)
BACKGROUND The aim of this study was to assess the use of neutrophil distribution width (NDW) and to compare it to C-reactive protein (CRP) and procalcitonin (PCT), in the detection of early sepsis in the intensive care unit. METHODS Subjects (N = 166) were divided into 4 groups: healthy, acute inflammatory non-infectious (AINI), localized infection, and(More)
OBJECTIVE This study aimed to investigate the effect of hormonal therapy (HRT) on voice in a group of menopausal women, taking into consideration body mass index (BMI) as a confounding factor and its potential role as a substitute for HRT. SUBJECTS AND METHODS A total of 53 menopausal women, 34 not on HRT and 19 on HRT, were recruited. Demographic(More)
Hyperhomocysteinemia is associated with several vascular and teratogenic conditions. Determinants of total homocysteine concentrations include genetic and nutritional factors. This study assesses the relation between homocysteine concentrations and MTHFR gene polymorphisms at two common alleles (C677T (rs1801133) and A1298C (rs1801131)) as well as other(More)
OBJECTIVE To report on the correlation between the length and projection of the upper and lower jaw and the fundamental frequency (F0). STUDY DESIGN Prospective study. MATERIALS AND METHODS A total of 45 healthy subjects were included in this study. The facial skeletal measurements included: SNA, SNB, ANB, angles that reflect the position of the maxilla(More)
OBJECTIVE To investigate the effect of vitamin D deficiency on the laryngopharyngeal tract. STUDY DESIGN Prospective cohort study. SETTING Tertiary care center. SUBJECTS AND METHODS A total of 38 human subjects were prospectively recruited, equally divided into two groups. The Vitamin D deficiency group defined as 25-OH<25ng/dl and the control(More)
OBJECTIVE Investigate the association between formants frequencies and length and sagittal projection of the maxilla and mandible. STUDY DESIGN Cross-sectional study. METHOD A total of 47 consecutive patients were recruited. Craniofacial measures included; maxillary length (ANS-PNS), mandibular length (Co-Gn), relationship between maxilla and mandible(More)
The aim of the study was to report on the prevalence and severity of laryngopharyngeal symptoms in patients with COPD compared to controls. A total of 27 patients with COPD and 13 controls matched according to age and gender were included. Demographic data included age, gender, history of smoking and history of allergic rhinitis. The Reflux symptom Index(More)
OBJECTIVES To compare the prevalence of phonatory symptoms in menopausal women compared to pre-menopause women with body mass index (BMI) as a confounding variable. METHODS A total of 69 women, 34 menopausal and 35 pre-menopausal were invited to participate in this study. Demographic variables included age, smoking, and BMI. All subjects were asked about(More)
Hereditary hemochromatosis (HHC) is a genetic disorder of iron metabolism characterized by abnormal accumulation of iron that may lead to organ damage and death. Diagnosis is usually based on various genetic and phenotypic criteria. The study goals were to perform mutation analysis for 18 different mutations associated with HHC in healthy Lebanese,(More)