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s The Journal of Pain S23 pain by using, for each subject, the pinprick force required to elicit an NRS of 5-7. The test could also be used to enrich the study group by including only those with good baseline pain sensitivity. A series of 6 pinpricks were then performed in 4 areas on the forearms. Between-subject mean pain scores were normally distributed(More)
ATTEMPTING to articulate his thoughts on the legal definition of obscenity in the 1960s, Supreme Court Justice Potter Stewart, opined “I know it when I see it.”* This approach, celebrated at that time as intuitive and pragmatic, was one he later recanted. Clinicians take a similar approach to situations that are often more complex than they appear. In this(More)
U ntil June, and for almost the past five years, I was IONA’s chief architect. On my first day, the head of human resources walked me around the office and introduced me as “our new senior architect.” Later that afternoon, a new colleague I had met earlier approached me with some confusion about my role. “After all,” he said as he looked at the walls and(More)
Not until recently have attitudes begun to change towards the cannabinoid medications, allowing substantial pre-clinical research to be undertaken to attempt to understand their mechanism of action. In the process of this undertaking, scientists confirmed the existence of an endocannabinoid system that regulates pain at every level of nociception. There is(More)
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