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- H. Böing, Angela Bechthold, +9 authors Bernhard Watzl
- European journal of nutrition
- 2012
BACKGROUND
Vegetables and fruit provide a significant part of human nutrition, as they are important sources of nutrients, dietary fibre, and phytochemicals. However, it is uncertain whether the risk… (More)
- Monika Julia Wolf, Arlind Adili, +24 authors Mathias Heikenwalder
- Cancer cell
- 2014
Hepatocellular carcinoma (HCC), the fastest rising cancer in the United States and increasing in Europe, often occurs with nonalcoholic steatohepatitis (NASH). Mechanisms underlying NASH and… (More)
- Anna Shkoda, Pedro Antonio Ruiz, +4 authors Dirk Haller
- Gastroenterology
- 2007
BACKGROUND & AIMS
The initiation of endoplasmic reticulum (ER)-mediated stress responses in intestinal epithelial cells (IEC) may contribute to the pathogenesis of chronic intestinal inflammation.… (More)
- Dirk Haller, H Colbus, Michael G Gänzle, P Scherenbacher, Cristiana Bode, Walter P. Hammes
- Systematic and applied microbiology
- 2001
Metabolic and functional properties of probiotic lactic acid bacteria (LAB) in the human gastro-intestinal ecosystem may be related to certain beneficial health effects. In this study, lactobacilli… (More)
BACKGROUND AND AIM
Intestinal epithelial cells (IEC) are thought to participate in the mucosal defence against bacteria and in the regulation of mucosal tissue homeostasis. Reactivity of IEC to… (More)
- Ilias Lagkouvardos, Divya Joseph, +4 authors Thomas Clavel
- Scientific reports
- 2016
The SRA (Sequence Read Archive) serves as primary depository for massive amounts of Next Generation Sequencing data, and currently host over 100,000 16S rRNA gene amplicon-based microbial profiles… (More)
- Martin Schlapschy, Uli Binder, +5 authors Arne Skerra
- Protein engineering, design & selection : PEDS
- 2013
A major limitation of biopharmaceutical proteins is their fast clearance from circulation via kidney filtration, which strongly hampers efficacy both in animal studies and in human therapy. We have… (More)
- Natalie Steck, Micha Hoffmann, +12 authors Dirk Haller
- Gastroenterology
- 2011
BACKGROUND & AIMS
Matrix metalloproteases (MMPs) mediate pathogenesis of chronic intestinal inflammation. We characterized the role of the gelatinase (GelE), a metalloprotease from Enterococcus… (More)
- Eva Rath, Emanuel Berger, +7 authors Dirk Haller
- Gut
- 2012
OBJECTIVE
Inflammatory bowel diseases (IBDs) feature multiple cellular stress responses, including endoplasmic reticulum (ER) unfolded protein responses (UPRs). UPRs represent autoregulatory pathways… (More)
- Ludovica F. Buttó, Monika Schaubeck, Dirk Haller
- Front. Immunol.
- 2015
Crohn's disease (CD) is a systemic chronic inflammatory condition mainly characterized by discontinuous transmural pathology of the gastrointestinal tract and frequent extraintestinal manifestations… (More)