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Stratification of head and neck squamous cell carcinomas (HNSCC) based on HPV16 DNA and RNA status, gene expression patterns, and mutated candidate genes may facilitate patient treatment decision. We characterize head and neck squamous cell carcinomas (HNSCC) with different HPV16 DNA and RNA (E6*I) status from 290 consecutively recruited patients by gene(More)
Negative pressure wound therapy (NPWT) has been used for a broad range of indications and wound types. However, it can be difficult to maintain an airtight dressing seal when the wound is located in an anatomically challenging area or environment. To address this problem, medical silicone, used to create intraoral vacuum dressings, was used in five patients(More)
The aim of this study is to investigate static and dynamic infrared (IR) thermography for intra- and postoperative free-flap monitoring following oropharyngeal reconstruction. Sixteen patients with oropharyngeal reconstruction by free radial forearm flap were included in this prospective, clinical study (05/2013–08/2014). Prior (“intraop_pre”) and following(More)
Die klinische Untersuchung einschließlich der Rhinoskopie ergab lediglich eine Nasenseptumdeviation nach links, eine Hyperplasie der unteren Nasenmuscheln rechts mehr als links und geringe Mengen trüben Sekrets in der linken Nasenhaupthöhle (oder der unteren Nasenmuschel). Die Mundschleimhaut, insbesondere im Bereich des linken Oberkiefers, war unauffällig,(More)
In extended cysts of the jaw bone particular demands are made in terms of wound closure, especially if an intraoral surgical approach is chosen. A tight closure is even more important if the bony defect has been filled with an alloplastic material or autologous cancellous bone. In our case a keratocyst of the left mandibular angle and ascending ramus was(More)
Paget´s disease of bone is a common, progressive disorder with uncertain etiology. It results in the replacement of normal skeletal areas with highly vascularized, low density bone. The most frequent symptom is bone pain, which is a result of periostal irritation due to increased metabolic activity. However, the disease may run without any symptoms. In(More)