T his current version provides a summary of recommendations for best practice in creating peritoneal access for patients on peritoneal dialysis (PD). A more detailed review of peritoneal access is available in the report from the Renal Association Working Party on Peritoneal Access (final version April 2008) available at www.renal.org. These guidelines are… (More)
OBJECTIVE This study reviews relevant publications on the peritoneal vasculature and tries to establish morphological-functional relationships. DESIGN The design is a review article. RESULTS Recent morphological studies in peritoneal dialysis (PD) patients have shown the presence of diabetiform neoangiogenesis in long-term peritoneal dialysis. The same… (More)
Transcellular water transport (TCWT) can be estimated by Na- sieving. However, the assumption that the initial Na+ dialysate concentration (D0) is equal to the initial plasma concentration (P0) is not true for each patient. The difference leads to Na+ diffusion from the circulation to the dialysate, which diminishes the Na+ sieving. A model was developed to… (More)
Encapsulating peritoneal sclerosis (EPS) is a rare but very severe complication of long-term peritoneal dialysis (PD). Since the first reports on this disease in the eighties, several imaging techniques have been used for its diagnosis. Because of the rarity of this condition, uniformity in modality and protocols for abdominal imaging for diagnosis has been… (More)
Background. Long-term peritoneal dialysis (PD) may lead to functional and morphologic changes in the peritoneal membrane, probably because of the continuous exposure to conventional dialysis solutions. Methods. The morphologic changes include neoangiogenesis and fibrosis. The authors of this article developed a long-term peritoneal exposure model in rats,… (More)
A review is given on peritoneal function, especially ultra-filtration and ultrafiltration failure followed by recommendations on how to translate pathophysiology into clinical practice. The subsequent consequences for management of peritoneal membrane function and for patient information are also included.
Background. Indirect methods can be used to provide valuable information about peritoneal structure and function for the indirect analysis of peritoneal membrane. Methods. The focus of this paper will be on the commonly available tools for this purpose. First, the value and clinical relevance of CA125 as a marker of mesothelial cell mass in peritoneal… (More)
The transperitoneal transport of macromolecules is dependent on both effective peritoneal surface area and intrinsic permeability of the peritoneum. For passage of small solutes, the effective surface area is the main determinant. We hypothesized that day-to-day variations in peritoneal clearances are caused by changes in the effective surface area and not… (More)