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Multiple genes and their variants that lend susceptibility to many diseases will play a major role in clinical routine. Genetics-based cost reduction strategies in diagnostic processes are important in the setting of multiple susceptibility genes for a single disease. Head and neck paraganglioma (HNP) is caused by germline mutations of at least three(More)
BACKGROUND & AIMS In the Active Ulcerative Colitis Trial (ACT)-1 and ACT-2, patients with ulcerative colitis treated with infliximab were more likely than those given placebo to have a clinical response, undergo remission, and have mucosal healing. We investigated the association between early improvement (based on endoscopy) and subsequent clinical(More)
To describe epidemiology and prognosis of head and neck cancer in Germany. We analyzed the Thuringian cancer registry database from 1996 to 2005. 3,821 cases with primary head and neck cancer were evaluated for patient’s characteristics, tumor stage, incidence, treatment, and trends in overall survival. During the period 1996–2005, the incidence of(More)
OBJECTIVES To evaluate population-based data on incidence of pediatric adenoidectomy and rate of revision surgery. METHODS A retrospective study of all adenoidectomies in children was performed in the year 2009 in all otolaryngology departments in one federal state, Thuringia, in Germany. Patients' characteristics, preoperative diagnostics and(More)
Although tonsil surgery is one of the most frequent otorhinolaryngological procedures, not many population-based regional or country-wide studies are published on the incidence of postoperative bleeding and its risk factors. 2,216 patients underwent tonsil surgery in 2012 in Thuringia, a federal state in Germany. Most frequent indications were recurrent(More)
INTRODUCTION The objective of this study was to examine patterns of care and survival in a population-based sample of patients with head neck cancer (HNC) who were treated in Thuringia, a federal state in Germany, between 1996 and 2011. METHODS Data of 6291 patients with primary HNC from the Thuringian cancer registry were used to evaluate for patient's(More)
Die posttherapeutische Bildgebung ist für die Planung und Erfolgskontrolle von Tumorpatienten essenziell. Dabei stehen prinzipiell aller bildgebenden Verfahren zur Verfügung, wobei der Schwerpunkt bei den Schnittbildverfahren Computertomographie (CT), Magnetresonanztomographie (MRT) und Positronenemissionstomographie-CT (PET-CT) liegt. Die Entwicklungen der(More)
Head and neck in situ carcinoma is seldom diagnosed. Our knowledge about in situ cancer is limited. This study describes the epidemiology and prognosis of head and neck in situ cancer in Thuringia, Germany. We analyzed the cancer data of the Thuringian cancer registry database from 1996 to 2005. The database contained 3821 patients with primary head and(More)
Die Erfahrung eines Behandlungsteams, Interdisziplinarität, die Qualität der Arzt-Patienten-Beziehung, der sinnvolle Einsatz moderner Technik und ein fundiertes Wissen um die Langzeitergebnisse bei Beobachtung und Behandlung bestimmen die Ergebnisqualität bei Patienten mit Vestibularisschwannomen. Der vorliegende Beitrag ist eine Zusammenstellung der(More)
Although salivary gland surgery for benign diseases is an integral part of clinical routine of head and neck surgeons, there is not many population-based data published on incidence and efficiency of this surgery. Parotidectomy was performed in 180 patients and submandibulectomy in 97 patients for benign diseases in eight otorhinolaryngology and two(More)