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In magnesium alloys, the components used modify the alloy properties. For magnesium implants in contact with bone, rare earths alloys are commonly examined. These were shown to have a higher corrosion resistance than other alloys and a high mechanical strength, but their exact composition is hard to predict. Therefore a reduction of their content could be(More)
In former studies the magnesium alloy LAE442 showed promising in vivo degradation behavior and biocompatibility. However, reproducibility might be enhanced by replacement of the rare earth composition metal " E " by only a single rare earth element. Therefore, it was the aim of this study to examine whether the substitution of " E " by neodymium (" Nd ")(More)
The aim of this study was to investigate the differences in the in vivo degradation behaviour of magnesium implants with various grain sizes and damaged surfaces. For this purpose, three different LAE442 magnesium implants were produced: cast, single and double extruded implants, in order to obtain different grain sizes. Furthermore, defects were positioned(More)
BACKGROUND Most studies on biodegradable magnesium implants published recently use magnesium-calcium-alloys or magnesium-aluminum-rare earth-alloys.However, since rare earths are a mixture of elements and their toxicity is unclear, a reduced content of rare earths is favorable. The present study assesses the in vivo biocompatibility of two new magnesium(More)
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