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The consistently growing field of bioinformatics exhibits the success of cooperative work in biology and computer science. The interaction between new experimental techniques gaining more and more data about molecular structures and processes and the knowledge how to prepare, structure, and analyze this data and even more to predict relations based on this(More)
In this paper we investigate the problem of finding a 2-connected spanning subgraph of minimal cost in a complete and weighted graph G. This problem is known to be APX-hard, for both the edge and the vertex connectivity case. Here we prove that the APX-hardness still holds even if one restricts the edge costs to an interval [1, 1 + ε], for an arbitrary(More)
OBJECTIVES To evaluate the relation of Tamm-Horsfall protein (THP) and citrate, both potent actors in the urinary stone forming process. METHODS Quantitative determination of THP in calcium oxalate (CaOx) stone-forming patients and healthy subjects was carried out according to the enzyme-linked immunosorbent assay method. RESULTS THP excretion in(More)
To understand the genesis of urinary stones different crystallization models have been developed to simulate the crystallization processes that occur at the beginning of the stone formation. In this study a laser probe working on the principle of the measurement of back-scattered light was mounted on a batch crystallization model, in which calcium oxalate(More)
BACKGROUND Detection of renal artery stenoses (RAS) by means of duplex Doppler ultrasound with direct scanning of the main renal arteries is subject to numerous limitations. Using semiquantitative analysis of the Doppler curve, which can be recorded from intrarenal arteries, it is possible to detect RAS unaffected by the problems of direct Doppler scanning(More)
In this paper we present an improved method for the selective and sensitive determination of oxalate in different matrices such as urine, plasma, and food. The method uses ion chromatography for the separation of anions. To overcome problems with interfering matrix-anions, colourings, and macromolecules, we used an inline enzyme-reactor (ER) containing(More)
OBJECTIVE Five methods for oxalate analysis in urine are compared with respect to reliability, accuracy, and practicability. RESULTS Suppressed and unsuppressed ionchromatography, as well as the enzymatic Sigma-Kit, achieve low coefficients of variation for the within-batch imprecision (1.1-8.0%) and between-day imprecision (1.6-7.2%). The results of(More)