Dionigi Salvati

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Dear Sirs, Reduction in the hepatic cytochrome P450 system activity has been described after a vaccination in previous studies [1, 2]. While the mechanism behind such reduction was explained as the consequence of the activity of inflammatory cytokines on the mRNA level of hepatic cytochromes [3], it is unclear what effect this interaction may have in the(More)
The human papilloma virus (HPV) vaccines were introduced to reduce the incidence of cervical cancer. The bivalent vaccine is effective against HPV-16, -18, -31, -33 and -45 while the quadrivalent vaccine is effective against HPV-16, 18, 31, 6 and 11 types. The immunisation, recommended for adolescent females, has led to high vaccine coverage in many(More)
To the Editor: Human papillomavirus (HPV) infection is one of the most common sexually transmitted infections worldwide.1 Although usually transient and asymptomatic, HPV infection can result in cervical cancer in some predisposed women,1 and thus, many programs have been developed to foster HPV immunization. People who are at a particularly high risk for(More)
Bacterial meningitis is an important source of mortality and morbidity worldwide. Data exist on specific vaccines against Streptococcus pneumoniae and Neisseria meningitidis indicating that they reduce the incidence of meningitis, yet comprehensive information on the trend of bacterial meningitis is still lacking. We analysed the Kids’ Inpatient Database(More)
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