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Caloric restriction is able to delay age-related neurodegenerative diseases and cognitive impairment. In this study, we analyzed the effects of old-onset caloric restriction that started at 18 months of age, in the number of neuropeptide Y (NPY)- and somatostatin (SS)-containing neurons of the hippocampal formation. Knowing that these neuropeptidergic(More)
PURPOSE To describe our experience in treating penile melanoma in 06 patients followed at our institution. MATERIALS AND METHODS Between 2004 and 2012 six consecutive patients with penile melanoma were treated at our Institution. Stage of the disease was classified according to the 2002 AJCC pathologic system. Melanoma in situ (TIS) was diagnosed in one(More)
Sur unprobì eme inverse de détermination de coefficients de diffusion Abstract The numerical simulation of nuclear waste storage requires the knowledge of the physical parameters of the geologic structure of the site in order to determine the impact of a possible propagation of radionucleides. Since those parameters (porosity, permeability, etc.) are not(More)
<b>Context:</b> Empirical studies are gaining recognition in the Software Engineering (SE) research community, allowing improved quality of research and accelerating the adoption of new technologies in the software market. However, empirical studies in this area are still limited. In order to foster empirical research in SE, it is essential to understand(More)
<b>Context</b>: Empirical studies are gaining recognition in the Software Engineering (SE) research community. In order to foster empirical research, it is essential understand the environments, guidelines, process, and other mechanisms available to support these studies in SE. <b>Goal</b>: Identifying the mechanisms used to support the empirical strategies(More)
OBJECTIVE To determine whether high-level athletes with patellar tendinopathy have diminished knee proprioceptive acuity. DESIGN Cross-sectional study. SETTING University research laboratory (institutional). PARTICIPANTS Twenty-one basketball and volleyball players with patellar tendinopathy (13 men and 8 women; mean age 24.5 ± 3.6; body mass index =(More)
ETL (Extract-Transform-Load) systems are formed by processes responsible for the extraction of data from several sources, cleaning and transforming it in accordance with some prerequisites of a data warehouse, and finally loading it in its multidimensional structures. ETL processes are the most complex tasks involved within the development of a Data(More)
Inverse PCR is a powerful tool for the rapid introduction of desired mutations at desired positions in a circular double-stranded DNA sequence. Here, custom-designed mutant primers oriented in the inverse direction are used to amplify the entire circular template with incorporation of the required mutation(s). By careful primer design it can be used to(More)
Data warehousing systems populating processes are responsible for loading their data repositories – the data warehouses – with information they extract from operational sources. The tasks that integrate these processes are the most complex ones that we can find in a data warehousing system. For a flawless implementation, modelling these processes previously(More)