Diogo Guimarães

Aline Lara2
Silvia Guatimosim2
2Aline Lara
2Silvia Guatimosim
2Robert Gros
2Rita Pires
1Marcus V. Gomez
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Overwhelming evidence supports the importance of the sympathetic nervous system in heart failure. In contrast, much less is known about the role of failing cholinergic neurotransmission in cardiac disease. By using a unique genetically modified mouse line with reduced expression of the vesicular acetylcholine transporter (VAChT) and consequently decreased(More)
A large-scale urban sensing platform, composed of multiple Data Collection Units (DCUs) equipped with sensor hardware scattered accross the city, allows pervasive monitoring of environmental parameters. Gathering sensor data from a number of disparate locations at a backend server can be supported by delay-tolerant services provided by existing vehicular(More)
Autonomic dysfunction is observed in many cardiovascular diseases and contributes to cardiac remodeling and heart disease. We previously reported that a decrease in the expression levels of the vesicular acetylcholine transporter (VAChT) in genetically-modified homozygous mice (VAChT KD(HOM)) leads to decreased cholinergic tone, autonomic imbalance and a(More)
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