Diogo Gonçalves

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This paper describes our participation on Task 7 of SemEval 2014, which fo-cused on the recognition and disambigua-tion of medical concepts. We used an adapted version of the Stanford NER system to train CRF models to recognize tex-tual spans denoting diseases and disorders , within clinical notes. We considered an encoding that accounts with non-continuous(More)
Nowadays, Cable TV operators provide their users multiple ways to watch TV content, such as Live TV and Video on Demand (VOD) services. In the last years, Catch-up TV has been introduced, allowing users to watch recent broadcast content whenever they want to. Understanding how the users interact with such services is important to develop solutions that may(More)
The detection of the activities of pathogen-encoded virulence factors by the innate immune system has emerged as a new paradigm of pathogen recognition. Much remains to be determined with regard to the molecular and cellular components contributing to this defense mechanism in mammals and importance during infection. Here, we reveal the central role of the(More)
Transgenic mice expressing the caspase-cleaved form of the tyrosine kinase Lyn (LynΔN) develop a TNFα-dependent skin disease that accurately recapitulates human psoriasis. Participation of lymphocytes in this disease was confirmed by backcrossing LynΔN mice on a Rag-1 deficient background. The present study was therefore conducted to analyze whether(More)
Sympathetic paragangliomas are rare catecholamine-secreting tumors of extra-adrenal origin, and their diagnosis in children is even more infrequent. They usually manifest as hypertension, palpitations, headache, sweating, and pallor. Malignant paragangliomas are identified by the presence of metastasis. Hemorrhagic stroke in the pediatric population is a(More)
A A A A ABSTRACT BSTRACT BSTRACT BSTRACT BSTRACT This paper discusses how to analyse quality management practices in public organizations. We argue that this is a rather complex issue, since there are few objective elements that allow accurate definitions and measures. However, if it is true that quality is related to the perception of something good, than(More)
Multiple myeloma (MM) evolves from a premalignant condition known as monoclonal gammopathy of undetermined significance (MGUS). However, the factors underlying the malignant transformation of plasmocytes in MM are not fully characterized. We report here that Eµ-directed expression of the antiapoptotic Bcl-B protein in mice drives an MM phenotype that(More)
Recommendation systems are being explored by Cable TV operators to improve user satisfaction with services, such as Live TV and Video on Demand (VOD) services. More recently, Catch-up TV has been introduced, allowing users to watch recent broadcast content whenever they want to. These services give users a large set of options from which they can choose(More)
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