Dingyan Chen

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BACKGROUND Many studies have investigated the association between the OPRM1 A118G polymorphism (rs1799971) and alcohol dependence, but the results were inconsistent. To better understand this relationship, ethnicity-specific meta-analyses were conducted. METHODS We retrieved all eligible studies published up to April 12, 2011 from the PubMed/MEDLINE,(More)
Several studies have assessed the association between genetic polymorphisms of DRD2 and DRD4 genes and opioid dependence risk, while the results were inconsistent. We performed a meta-analysis, including 6,846 opioid dependence cases and 4,187 controls from 22 individual studies, to evaluate the roles of four variants (DRD2 -141ins/delC, rs1799732; DRD2 311(More)
BACKGROUND Injuries impact adolescents and young adults in unique ways. The purpose of this study was to determine the incidence rate of nonfatal injuries, and identify characteristics and risk factors for the injuries among adolescents and college students in Shenzhen, China. METHODS A total of 4,138 students from 79 classes were selected using a(More)
BACKGROUND Several studies have assessed the association between genetic polymorphisms of tryptophan hydroxylase (TPH1) and risk of mood disorders and alcohol dependence, with controversial results. Our aim was to assess the association of TPH1 A218C polymorphism (rs1800532) with mood disorders, including major depressive disorder and bipolar disorder, and(More)
PURPOSE To identify the annual prevalence and potential risk factors of nonfatal agricultural machinery injuries among agricultural machinery operators in the northern areas of China. METHODS A quota sampling method was used to study 1921 agricultural machinery operators in 5 provinces in northern China. Agricultural machinery injuries that occurred(More)
Rigorous validation of the popular obsessive compulsive drug use scale (OCDUS) has been sparse, while the lack of valid and reliable measurement scales continues to be an obstacle to the study and control of heroin addiction in China. Based on data from 295 randomly-selected male Chinese heroin addicts, we examined the psychometric properties of the OCDUS(More)
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