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OBJECTIVE The purpose of this study was to test the hypothesis that subjective angiographic endpoints during transarterial chemoembolization (TACE) of hepatocellular carcinoma are consistent and correlate with objective intraprocedural reductions in tumor perfusion determined with quantitative 4D transcatheter intraarterial perfusion MRI. SUBJECTS AND(More)
PURPOSE To develop a fully quantitative 4D transcatheter intraarterial perfusion (TRIP) magnetic resonance imaging (MRI) technique and prospectively test the hypothesis that quantitative 4D TRIP-MRI can be used clinically to monitor intraprocedural liver tumor perfusion reductions during transcatheter arterial chemoembolization (TACE). MATERIALS AND(More)
PURPOSE Transcatheter arterial chemoembolization (TACE) is an established treatment for unresectable liver cancer. This study was conducted to test the hypothesis that angiographic endpoints during TACE are measurable and reproducible by comparing subjective angiographic versus objective magnetic resonance (MR) endpoints of TACE. MATERIALS AND METHODS The(More)
OBJECTIVE The purpose of this study was to investigate the relation between angiographic embolic endpoints of transarterial chemoembolization (TACE) and the survival of patients with hepatocellular carcinoma (HCC). MATERIALS AND METHODS This study was a retrospective assessment of the cases of 105 patients with surgically unresectable HCC who underwent(More)
PURPOSE To prospectively test the hypothesis that transcatheter intraarterial first-pass perfusion (TRIP) magnetic resonance (MR) imaging can depict serial reductions in rabbit liver tumor perfusion during transcatheter arterial embolization (TAE). MATERIALS AND METHODS All experiments had institutional animal care and use committee approval. In four(More)
PURPOSE To determine the suitability of the rabbit VX2 tumor animal model for uterine fibroids and uterine artery embolization (UAE). MATERIALS AND METHODS The authors implanted and grew one uterine VX2 tumor per rabbit in six rabbits. UAE was performed by using 100-300 microm embolic particles and confirmed with x-ray digital subtraction angiography,(More)
PURPOSE To test the hypothesis that catheter-directed intraarterial (IA) contrast agent injection increases tumor enhancement and conspicuity compared to intravenous (IV) injection. MATERIALS AND METHODS Eight VX2 liver tumors were grown in five rabbits. After positioning a catheter in the hepatic artery, we performed 3D inversion recovery GRE MRI after(More)
A new method is presented for rapid and accurate large volumetric radiofrequency (RF) field (B(1) (+)) mapping. This method is a modification of the double-angle method (DAM), which accelerates imaging speed and applies 3D acquisition to improve B(1) (+) measurement accuracy. It reduces repetition time and scan time by introducing a catalyzation RF pulse(More)
PURPOSE An animal model of pancreatic cancer that is large enough to permit imaging and catheterization would be desirable for interventional radiologists to develop novel therapies for pancreatic cancer. The purpose of this study was to test the hypothesis that the VX2 rabbit model of pancreatic cancer could be developed as a suitable platform to test(More)
PURPOSE To prospectively test the hypothesis that intraprocedural transcatheter intraarterial perfusion (TRIP) magnetic resonance (MR) imaging can be used to successfully measure reductions in perfusion to the targeted hepatocellular carcinoma (HCC) and the adjacent surrounding liver tissue during MR-interventional radiology (IR)-monitored transcatheter(More)