Dingding Liu

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In this paper we develop and analyze spiking neural network (SNN) versions of resilient propagation (RProp) and QuickProp, both training methods used to speed up training in artificial neural networks (ANNs) by making certain assumptions about the data and the error surface. Modifications are made to both algorithms to adapt them to SNNs. Results generated(More)
We propose a novel and fast interactive image segmentation algorithm for use on mobile phones. Instead of using global optimization, our algorithm begins with an initial over-segmentation using the mean shift algorithm and follows this by discriminative clustering and local neighborhood classification. This procedure obtains better quality results than(More)
We propose an effective image segmentation approach with a novel automatic boundary refinement procedure that requires little user interaction and makes the object cutout process more robust and convenient. It achieves these goals by the following three steps. First, merge over-segmented regions according to the maximal similarity rule using a few marking(More)
The present study was aimed to investigate the effects of DNS on the structure of nasal cavity. The paranasal sinus coronal view CT of 108 patients with DNS and 129 hospitalized patients without DNS was retrospectively analyzed. The transverse diameter of nasal cavity (a), transverse diameter of nasal cavity and paranasal sinus (b), angle between maxillary(More)
Aminoglycosides are toxic to sensory hair cells (HCs). Macroautophagy/autophagy is an essential and highly conserved self-digestion pathway that plays important roles in the maintenance of cellular function and viability under stress. However, the role of autophagy in aminoglycoside-induced HC injury is unknown. Here, we first found that autophagy activity(More)
The aim of the present study was to investigate the underlying mechanisms of autophagy in a gentamicin (GM)-induced ototoxic model, and to establish whether the blocking of autophagy significantly increases the survival of inner ear hair cells. Cochleae were carefully dissected from four day‑old C57BL/6J mice and randomly divided into three groups prior to(More)
Hearing loss is a common sensory disorder mainly caused by the loss of hair cells (HCs). Noise, aging, and ototoxic drugs can all induce apoptosis in HCs. Apoptosis repressor with caspase recruitment domain(ARC) is a key factor in apoptosis that inhibits both intrinsic and extrinsic apoptosis pathways; however, there have been no reports on the role of ARC(More)
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