Dinesh Singhal

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Solid-pseudopapillary neoplasms (SPNs) of the pancreas are increasingly diagnosed, but the exact surgical management in terms of extent of the resection is not well defined. Patients operated on in our hospital between January 1993 and March 2005 formed the study groups. From 659 consecutive resections for pancreatic neoplasms, 12 female patients (1.8%)(More)
Around 80% of the patients with hilar cholangiocarcinoma are candidates for palliative management due to extensive co-morbidity for major surgery, metastases or advanced loco-regional disease. The primary aim of treatment is to provide biliary drainage with long-term relief from pruritus, cholangitis, pain and jaundice. Endoscopically placed self-expanding(More)
Sinistral portal hypertension is a clinical syndrome of gastric variceal hemorrhage in the setting of splenic vein thrombosis due to a primary pancreatic pathology. The distinguishing features from other forms of portal hypertension are preserved liver function and a patent extrahepatic portal vein. The important causes include acute and chronic(More)
OBJECTIVES Pancreatic fistula (PF) predicts mortality and morbidity in patients undergoing pancreaticoduodenectomy (PD). This study aimed to assess whether isolated Roux loop pancreaticojejunostomy (IPJ) is superior to conventional pancreaticojejunostomy (CPJ). METHODS Between September 2003 and July 2007, we performed 108 PDs. All patients underwent(More)
BACKGROUND Esophagogastric devascularization is an operation that can be performed for endoscopically uncontrolled variceal bleeding in hospitals having only basic surgical instruments and is therefore an appropriate procedure for small hospitals in developing countries. The aim of this study was to analyze one hospital's experience of this operation in(More)
The aim of the present study was to determine whether supplementation of resveratrol, a stilbenoid antioxidant with therapeutic significance, influences goat (Capra hircus) oocyte maturation and subsequent embryonic development and expression of apoptosis and early embryonic development-related genes. Five different concentrations of resveratrol (0.1, 0.25,(More)
Pancreatic pseudocysts (PPs) comprise more than 80% of the cystic lesions of the pancreas and cause complications in 7-25% of patients with pancreatitis or pancreatic trauma. The first step in the management of PPs is to exclude a cystic tumor. A history of pancreatitis, no septation, solid components or mural calcification on CT scan and high amylase(More)
In the present study we have investigated the effect of zinc oxide (ZnO) nanoparticles on the fiber diameter, fiber morphology, antibacterial activity, and enhanced cell proliferation of the electrospun polycaprolactone (PCL) non-woven membrane. The effect of the ZnO nanoparticle concentration on the fiber diameter and fiber morphology was investigated(More)
We read with interest the article by Johnson et al. in the August issue of the World Journal of Surgery. The authors retrospectively evaluated the outcomes of singlestaged transabdominal devascularization procedures with (group I) or without (group II) esophageal transection, in a selected group of 52 patients (Child A or B classification, unshuntable(More)
BACKGROUND/AIMS Using technology-intensive postoperative critical care, interventional radiology and consequent better management of pancreaticojejunal anastomosis (PJA) leaks, the perioperative mortality of pancreaticoduodenal resection (PDR) at high volume Western centers ranges from 1-5%. Facilities for such sophisticated care are not available in most(More)