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Synthesis of 68Ga-labeled DOTA-nitroimidazole derivatives and their feasibilities as hypoxia imaging PET tracers.
Two nitroimidazole derivatives were synthesized by conjugating nitroIMidazoles and 1,4,7,10-tetraazacyclodododecane-1,4-7, 10-Tetraacetic acid (DOTA) via an amide bond and a thiourea bond and both showed higher uptake in cancer cell lines cultured under hypoxic condition than under normoxic condition. Expand
Cucurbit[6]uril-based polymer nanocapsules as a non-covalent and modular bioimaging platform for multimodal in vivo imaging
Cucurbit[6]uril (CB[6])-based polymer nanocapsules (CB[6]PNs) were used as a multimodal platform for cancer-targeted in vivo bioimaging. By taking advantage of the strong and robust host–guestExpand
Eliminating the Heart from the Curcumin Molecule: Monocarbonyl Curcumin Mimics (MACs)
The present review focuses on the large and evolving body of work in cancer and inflammation, but also covers MAC structural diversity and early discovery for treatment of bacteria, tuberculosis, Alzheimer’s disease and malaria. Expand
Stable aluminium fluoride chelates with triazacyclononane derivatives proved by X-ray crystallography and 18F-labeling study.
A single crystal structure of an aluminium-fluoride complex of a model compound (NODA-benzyl) was studied to understand the co-ordination chemistry. Series of ligands with an extra carboxylic acidExpand
Synthesis and characterization of nitroimidazole derivatives for 68Ga-labeling and testing in tumor xenografted mice.
(68)Ga labeled NI derivatives for hypoxic tissue imaging were successfully developed and it was proved that amide oxygen of Ga-NOTA-NI contributes to the formation of metal complex by X-ray crystallography. Expand
Redox-Responsive Covalent Organic Nanosheets from Viologens and Calix[4]arene for Iodine and Toxic Dye Capture.
The use of diazo coupling is described to synthesize two cationic COPs, COP1++ and COP2++ , that incorporate a viologen-based molecular switch and an organic macrocycle, calix[4]arene, that exhibit high affinity for iodine, which makes the materials among the best-performing nanosheets for iodine capture reported in the literature. Expand
Formation and Characterization of Gallium(III) Complexes with Monoamide Derivatives of 1,4,7‐Triazacyclononane‐1,4,7‐triacetic Acid: A Study of the Dependency of Structure on Reaction pH
Two monoamide derivatives of 1,4,7-triazacyclononane-1,4,7-triacetic acid (NOTA) conjugated with methylamine (4) or benzylamine (5) were synthesized by treating di-tert-butylExpand
Can we beat the biotin-avidin pair?: cucurbit[7]uril-based ultrahigh affinity host-guest complexes and their applications.
The progress in the development of high affinity guests for CB[7], factors affecting the stability of complexes, theoretical insights, and the utility of these high affinity pairs in different challenging applications are summarized. Expand
Porous Polycalix[4]arenes for Fast and Efficient Removal of Organic Micropollutants from Water.
The utility of porous calixarene-based materials, CalPn, for water purification can be regenerated several times, with performance levels left undiminished, by a simple wash procedure that is less energy intensive than that required for ACs. Expand