Dimitros G. Oreopoulos

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The aim of this study was to characterize the differences between the prediction of GFR with Cockcroft-Gault formula (CG=(140–age)/(72×PCr (mg/ml), for females multiplied by 0.85) and the new formula based on the multicenter trial of the Modification of Diet in Renal Diseases (MDRD=186 × P Cr −1.154 × age−0.203; 0.742 if patient is female) in elderly(More)
In this retrospective study we present our experience with chronic peritoneal dialysis in nine patients with ESRD in their 10th decade of life (≥90 years) at the Toronto Western Hospital. A family member or a private nurse assisted all patients in dialysis procedure. The co-morbid illnesses, survival, hospitalizations and complications related or unrelated(More)
High Body Mass Index (BMI) has been associated with improved survival of End-Stage Renal Disease (ESRD) patients on chronic hemodialysis (HD); however, studies on the relationship of BMI with survival in Peritoneal Dialysis (PD) patients have yielded conflicting results. The purpose of this study was to evaluate the impact of BMI on survival of Canadian(More)
Pyridoxine in doses of 250–500 mg daily by mouth was administered to 12 patients suffering from recurrent calcium oxalate renal calculi and idiopathic hyperoxaluria. This therapy decreased urinary oxalate excretion significantly (p<0.025) during up to 18 months of treatment. In that period eight patients showed no evidence of active stone disease; three(More)
Schiavon et al. (1994) have reported that the measurement of plasma glutathione peroxidase activity (PGP) could provide an index of renal function. Its activity, which was depressed in patients with impaired renal function, correlated positively with creatinine clearance and negatively with serum creatinine. To evaluate the hypothesis that the plasma PGP(More)
Renal cell carcinoma is a rare but seriouscomplication in ESRD patients. In thesepatients the incidence of renal cell carcinoma(RCC) is 20–40 times higher than in thegeneral population. We performed aretrospective study to measure the incidencerate, prevalence, characteristics and survivalamong our peritoneal dialysis (PD) patientsdiagnosed with renal cell(More)
Previous studies have shown that life-long caloric restriction in rats protects the kidneys from age-dependent injury. In this study, we analyzed whether late-life-introduced caloric restriction has a similar effect. The study lasted 12 months. Three groups of animals were analyzed: rats fed “ad libitum” (AD, n = 9), rats on 60% caloric restriction (CR, n =(More)
Objective: To analyze the effect of age on nutrition indices in subjects on the same continuous ambulatory peritoneal dialysis (CAPD) schedule. Methods: We analyzed 613 sets of clearance values and nutrition indices in 302 CAPD patients. Small solute clearances included urea clearance (Kt/Vurea) and creatinine clearance (Ccr). Nutrition indices included(More)
Editor, We thank Dr. Onuigbo for his comments concerning our report on glomerular filtration rate (GFR) stage variability in patients with chronic kidney disease [1]. Dr. Onuigbo supports the notion that medication changes, and in particular changes in inhibitors of the renin–angiotensin–aldosterone system, contribute to the observed variation in renal(More)
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