Dimitris Karalekas

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In this paper, a combined experimental-numerical based work was undertaken to investigate the Bragg wavelength shift response of an embedded FBG sensor when subjected to different conditions of multi-axial loading (deformation). The following cases are examined: (a) when an isotropic host material with no constrains on planes normal to the embedded sensor's(More)
We report on the design, modeling and fabrication by multi-photon polymerization of a complex medical fluidic device. The physical dimensions of the built micro-valve prototype are compared to those of its computer-designed model. Important fabrication issues such as achieving high dimensional resolution and ability to control distortion due to shrinkage(More)
The isolated ciliary epithelium contains barium-inhibitable potassium channels. The present study was aimed at testing the in vivo effects of barium on aqueous humor dynamics in rabbits. BaCl2 was administered to one eye by topical delivery or intravitreal injection. Dynamic measurements included intraocular pressure, outflow facility, episcleral venous(More)
PURPOSE To compare the efficacy of 0.5% and 1.0% apraclonidine in preventing laser-induced intraocular pressure (IOP) elevation after trabeculoplasty, neodymium: YAG (Nd: YAG) iridotomy, and capsulotomy. METHODS This is a prospective, masked, and randomized study of 83 patients undergoing trabeculoplasty, 62 patients undergoing iridotomy, and 57 patients(More)
In this work, the mechanical behaviour of a photocured Ormocomp(®) hybrid material is investigated. Its biocompatible nature has attracted a growing interest for microfabrication applications in biomedicine and tissue engineering. Measurements of in situ solidification strain development and achieved degree of curing, as obtained using a fibre optic sensor,(More)
This study initially deals with the investigation of the induced strains during hardening stage of a self-setting calcium phosphate bone cement using fiber-Bragg grating (FBG) optical sensors. A complementary Scanning Electron Microscopy (SEM) investigation was also conducted at different time intervals of the hardening period and its findings were related(More)
PURPOSE To investigate physiological and histologic alterations of the cat eye in response to cyclocryotherapy (CCT) and noncontact transscleral Nd:YAG laser cyclophotocoagulation (TSNYC). METHODS One eye of 29 cats was treated with 12 applications (1 minute, -80 degrees C) of CCT or 80 applications of noncontact TSNYC (7 to 9 J, retrofocus 3.6 mm).(More)
OBJECTIVE To perform a mechanical characterization of a self-setting calcium phosphate cement in function of the immersion time in Ringer solution. MATERIALS AND METHODS Specimens of self-setting calcium phosphate cement were prepared from pure α-TCP powder. The residual strains developed during hardening stage were monitored using an embedded fiber Bragg(More)
A novel computational intelligence methodology is proposed for identifying the properties of maximally sustainable materials for any given application; identification is based on the known properties of existing candidate materials. Once the correlation surface between material properties and environmental impact values of the candidate materials is created(More)
Quasi-elastic light scattering spectroscopy was used to non-invasively monitor affects of transient blood glucose changes on lenses of non-diabetic subjects undergoing glucose tolerance testing and diabetic subjects undergoing glucose clamping protocols. Non-diabetic subjects exhibited a characteristic biphasic change in lens protein diffusion coefficient(More)