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  • Norbert W Brattig, Chiara Bazzocchi, +9 authors Achim Hoerauf
  • Biology, Medicine
  • The Journal of Immunology
  • 2004 (First Publication: 1 July 2004)
  • More than 150 million humans in tropical countries are infected by filarial nematodes which harbor intracellular bacterial endosymbionts of the genus Wolbachia (Rickettsiales). These bacteria haveExpand
  • Achim Hoerauf, Sabine Specht, +13 authors Dietrich W. Büttner
  • Biology, Medicine
  • Medical Microbiology and Immunology
  • 2007 (First Publication: 13 November 2007)
  • In a randomized, placebo-controlled trial in Ghana, 67 onchocerciasis patients received 200-mg/day doxycycline for 4–6 weeks, followed by ivermectin (IVM) after 6 months. After 6–27 months, efficacyExpand
  • Achim Hoerauf, S Farah Mand, +6 authors Dietrich W. Büttner
  • Biology, Medicine
  • Medical Microbiology and Immunology
  • 2003 (First Publication: 1 November 2003)
  • Chemotherapy of onchocerciasis by doxycycline, which targets symbiotic Wolbachia endobacteria, has been shown to result in a long-term sterility of adult female worms and corresponding absence ofExpand
  • Norbert W Brattig, B Lepping, +4 authors Rolf Dieter Horstmann
  • Biology, Medicine
  • The Journal of infectious diseases
  • 2002 (First Publication: 15 April 2002)
  • The cellular immune response to Onchocerca volvulus antigen (OvAg) was studied in 551 persons exposed to O. volvulus transmission in a hyperendemic area of Ghana, West Africa. A whole-blood assayExpand